Detailed information NTG0795247

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH63_RS05095
• Genome accession: NZ_CP118788
• Coordinates: 1074142..1075185 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain 7070
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1069142..1080185

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH63_RS05070 (PYH63_05025)	-	1069282..1070004 (+)	723	WP_096597671.1	glutamine amidotransferase	-
PYH63_RS05075 (PYH63_05030)	-	1071088..1072086 (-)	999	WP_262611975.1	aromatic acid exporter family protein	-
PYH63_RS05080 (PYH63_05035)	map	1072183..1072944 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
PYH63_RS05085 (PYH63_05040)	-	1073042..1073431 (+)	390	WP_262611976.1	hypothetical protein	-
PYH63_RS05090 (PYH63_05045)	liaF	1073444..1074145 (+)	702	WP_096597675.1	cell wall-active antibiotics response protein LiaF	-
PYH63_RS05095 (PYH63_05050)	vraS	1074142..1075185 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
PYH63_RS05100 (PYH63_05055)	vraR	1075175..1075804 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
PYH63_RS05105 (PYH63_05060)	-	1076438..1077019 (-)	582	WP_096597677.1	carbonic anhydrase	-
PYH63_RS05110 (PYH63_05065)	-	1077052..1078398 (-)	1347	WP_262611979.1	YhjD/YihY/BrkB family envelope integrity protein	-
PYH63_RS05115 (PYH63_05070)	-	1078614..1078901 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
PYH63_RS05120 (PYH63_05075)	-	1078909..1079367 (-)	459	WP_262611980.1	low molecular weight protein-tyrosine-phosphatase	-
PYH63_RS05125 (PYH63_05080)	-	1079501..1079704 (+)	204	WP_019169369.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=795247 PYH63_RS05095 WP_019166463.1 1074142..1075185(+) (vraS) [Staphylococcus delphini strain 7070]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=795247 PYH63_RS05095 WP_019166463.1 1074142..1075185(+) (vraS) [Staphylococcus delphini strain 7070]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTAAGACCTATAGGATTGAAGG
ATAAATCGTTAGGTGAGGGGATAAAATCGCTCGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACAGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836