Detailed information NTG0794037

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: PWF74_RS00725
• Genome accession: NZ_CP118627
• Coordinates: 149928..152378 (+)
• Length: 816 a.a.
• NCBI ID: WP_207784790.1
• Uniprot ID: A0AAX3NF06
• Organism: Lactococcus garvieae strain Pa-2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 144928..157378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PWF74_RS00700 (PWF74_00700)	-	145835..146347 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
PWF74_RS00705 (PWF74_00705)	rpoE	146485..147045 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
PWF74_RS00710 (PWF74_00710)	mltG	147151..148866 (+)	1716	WP_003134003.1	endolytic transglycosylase MltG	-
PWF74_RS00715 (PWF74_00715)	greA	148891..149364 (+)	474	WP_003134005.1	transcription elongation factor GreA	-
PWF74_RS00720 (PWF74_00720)	-	149486..149938 (+)	453	WP_003134006.1	CtsR family transcriptional regulator	-
PWF74_RS00725 (PWF74_00725)	clpC	149928..152378 (+)	2451	WP_207784790.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
PWF74_RS00730 (PWF74_00730)	hpf	152502..153059 (+)	558	WP_003134010.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
PWF74_RS00735 (PWF74_00735)	pflB	153307..155640 (+)	2334	WP_003134012.1	formate C-acetyltransferase	-
PWF74_RS00740 (PWF74_00740)	coaE	155872..156477 (+)	606	WP_003134016.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91119.37 Da
• Isoelectric Point: 6.1755

>NTDB_id=794037 PWF74_RS00725 WP_207784790.1 149928..152378(+) (clpC) [Lactococcus garvieae strain Pa-2]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=794037 PWF74_RS00725 WP_207784790.1 149928..152378(+) (clpC) [Lactococcus garvieae strain Pa-2]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTTGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGCCCAAGAGTTGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAACCGTATTGGGAC
AGAACATCTCTTGTATATGCTGTTGGCGAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATTG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACTCCAGCCTCAAAA
AGAAATCTGTCGGGGAAGGTGTCCGAAACAACAACAACGCCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGCAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGAACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCCATTATTGAAGGCTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGTGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAAGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGTTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTACGACGAAGGAGGACAATTGACAGAAC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGACATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAGGTTGATTTCCGAAATACAATCATCATTATGACATC
CAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATCGATGAAACCATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATCACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGAAATTCATCCGGGGGATACG
ATTTCTATTGGGTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.798	99.877	0.707
clpC	Streptococcus thermophilus LMG 18311	49.819	100	0.505
clpC	Streptococcus thermophilus LMD-9	49.819	100	0.505
clpC	Streptococcus pneumoniae TIGR4	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.274	100	0.499
clpC	Streptococcus pneumoniae D39	49.274	100	0.499
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.31	97.917	0.473
clpE	Streptococcus mutans UA159	46.875	78.431	0.368