Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PWA59_RS05790 Genome accession   NZ_CP118541
Coordinates   1116671..1117327 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain HC-5     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1111671..1122327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWA59_RS05765 (PWA59_05765) oppF 1112201..1113118 (+) 918 WP_014417419.1 oligopeptide ABC transporter ATP-binding protein OppF -
  PWA59_RS05770 (PWA59_05770) - 1113225..1114421 (+) 1197 WP_014417420.1 putative glycoside hydrolase -
  PWA59_RS05775 (PWA59_05775) - 1114530..1115108 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  PWA59_RS05780 (PWA59_05780) spx 1115287..1115682 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  PWA59_RS05785 (PWA59_05785) - 1115739..1116395 (-) 657 WP_014417421.1 TerC family protein -
  PWA59_RS05790 (PWA59_05790) mecA 1116671..1117327 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  PWA59_RS05795 (PWA59_05795) - 1117479..1118639 (+) 1161 WP_014417422.1 competence protein CoiA family protein -
  PWA59_RS05800 (PWA59_05800) pepF 1118867..1120696 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  PWA59_RS05805 (PWA59_05805) - 1120734..1120901 (-) 168 WP_003155026.1 hypothetical protein -
  PWA59_RS05810 (PWA59_05810) spxH 1121188..1122090 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=793092 PWA59_RS05790 WP_003155032.1 1116671..1117327(+) (mecA) [Bacillus velezensis strain HC-5]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=793092 PWA59_RS05790 WP_003155032.1 1116671..1117327(+) (mecA) [Bacillus velezensis strain HC-5]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCAAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895