Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   PVK50_RS01790 Genome accession   NZ_CP118311
Coordinates   338203..338793 (+) Length   196 a.a.
NCBI ID   WP_002985850.1    Uniprot ID   A0A9X8T4H8
Organism   Streptococcus pyogenes strain 20164915     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 333203..343793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK50_RS01775 (PVK50_01760) - 334015..335460 (-) 1446 WP_002990934.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  PVK50_RS01780 (PVK50_01765) - 335548..337182 (+) 1635 WP_002990932.1 polysaccharide biosynthesis protein -
  PVK50_RS01785 (PVK50_01770) upp 337350..337979 (+) 630 WP_002985854.1 uracil phosphoribosyltransferase -
  PVK50_RS01790 (PVK50_01775) clpP 338203..338793 (+) 591 WP_002985850.1 ATP-dependent Clp protease proteolytic subunit Regulator
  PVK50_RS01795 (PVK50_01780) - 339288..339581 (+) 294 WP_002990928.1 YlbG family protein -
  PVK50_RS01800 (PVK50_01785) - 339841..340974 (+) 1134 WP_397610647.1 ISAs1-like element IS1548 family transposase -
  PVK50_RS01805 (PVK50_01795) tmk 341137..341772 (+) 636 WP_002990917.1 dTMP kinase -
  PVK50_RS01810 (PVK50_01800) - 341790..342665 (+) 876 WP_002990914.1 DNA polymerase III subunit delta' -
  PVK50_RS01815 (PVK50_01805) yabA 343329..343652 (+) 324 WP_002985838.1 DNA replication initiation control protein YabA -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21648.88 Da        Isoelectric Point: 5.2834

>NTDB_id=791738 PVK50_RS01790 WP_002985850.1 338203..338793(+) (clpP) [Streptococcus pyogenes strain 20164915]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=791738 PVK50_RS01790 WP_002985850.1 338203..338793(+) (clpP) [Streptococcus pyogenes strain 20164915]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACTAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCGGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pyogenes MGAS315

100

100

1
  clpP Streptococcus pyogenes JRS4

100

100

1
  clpP Streptococcus mutans UA159

90.816

100

0.908
  clpP Streptococcus pneumoniae Rx1

90.769

99.49

0.903
  clpP Streptococcus pneumoniae D39

90.769

99.49

0.903
  clpP Streptococcus pneumoniae R6

90.769

99.49

0.903
  clpP Streptococcus pneumoniae TIGR4

90.769

99.49

0.903
  clpP Streptococcus thermophilus LMG 18311

89.796

100

0.898
  clpP Streptococcus thermophilus LMD-9

89.796

100

0.898
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

86.224

100

0.862
  clpP Lactococcus lactis subsp. cremoris KW2

85.714

100

0.857
  clpP Bacillus subtilis subsp. subtilis str. 168

57.143

100

0.571
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.995

98.469

0.561