Detailed information NTG0790929

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: Q7627_RS04560
• Genome accession: NZ_CP131706
• Coordinates: 886514..887164 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387329.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2018N21-288
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 881514..892164

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7627_RS04535 (Q7627_04530)	-	882037..882537 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
Q7627_RS04540 (Q7627_04535)	-	882540..882866 (+)	327	Protein_895	TfoX/Sxy family protein	-
Q7627_RS04545 (Q7627_04540)	ald	883167..884254 (-)	1088	Protein_896	alanine dehydrogenase	-
Q7627_RS04550 (Q7627_04545)	-	884288..885544 (-)	1257	WP_000530081.1	ISL3 family transposase	-
Q7627_RS04555 (Q7627_04550)	-	885877..886446 (+)	570	WP_000443772.1	GNAT family N-acetyltransferase	-
Q7627_RS04560 (Q7627_04555)	comEA/celA/cilE	886514..887164 (+)	651	WP_000387329.1	helix-hairpin-helix domain-containing protein	Machinery gene
Q7627_RS04565 (Q7627_04560)	comEC/celB	887148..889388 (+)	2241	WP_000942408.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
Q7627_RS04570 (Q7627_04565)	-	889567..889755 (+)	189	WP_001810030.1	hypothetical protein	-
Q7627_RS04575 (Q7627_04570)	-	889788..890375 (+)	588	WP_000939886.1	ABC transporter ATP-binding protein	-
Q7627_RS04580 (Q7627_04575)	-	890379..891563 (+)	1185	WP_000655949.1	ABC transporter permease	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23254.66 Da
• Isoelectric Point: 5.9204

>NTDB_id=790929 Q7627_RS04560 WP_000387329.1 886514..887164(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 2018N21-288]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVHKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=790929 Q7627_RS04560 WP_000387329.1 886514..887164(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 2018N21-288]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCATAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAATCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterProScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae D39	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae R6	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.37	100	0.954
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361