Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   MGCS35823_RS05955 Genome accession   NZ_CP117289
Coordinates   1149363..1150673 (-) Length   436 a.a.
NCBI ID   WP_014612303.1    Uniprot ID   A0A9X8T438
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1144363..1155673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35823_RS05925 (MGCS35823_02402) - 1144798..1145187 (-) 390 WP_003058840.1 cytidine deaminase -
  MGCS35823_RS05930 (MGCS35823_02404) deoC 1145174..1145836 (-) 663 WP_015017040.1 deoxyribose-phosphate aldolase -
  MGCS35823_RS05935 (MGCS35823_02406) - 1145852..1147129 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  MGCS35823_RS05940 (MGCS35823_02408) - 1147116..1147715 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  MGCS35823_RS05945 (MGCS35823_02410) coaA 1147983..1148903 (+) 921 WP_084916836.1 type I pantothenate kinase -
  MGCS35823_RS05950 (MGCS35823_02412) rpsT 1148957..1149205 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  MGCS35823_RS05955 (MGCS35823_02414) ciaH 1149363..1150673 (-) 1311 WP_014612303.1 HAMP domain-containing sensor histidine kinase Regulator
  MGCS35823_RS05960 (MGCS35823_02416) ciaR 1150666..1151340 (-) 675 WP_014612304.1 response regulator transcription factor Regulator
  MGCS35823_RS05965 (MGCS35823_02418) - 1151544..1154081 (-) 2538 WP_084916834.1 M1 family metallopeptidase -
  MGCS35823_RS05970 (MGCS35823_02420) phoU 1154282..1154935 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49918.49 Da        Isoelectric Point: 8.2375

>NTDB_id=783448 MGCS35823_RS05955 WP_014612303.1 1149363..1150673(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSIDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=783448 MGCS35823_RS05955 WP_014612303.1 1149363..1150673(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTATCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGACGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514