Detailed information NTG0783030

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PQQ27_RS09615
• Genome accession: NZ_CP117238
• Coordinates: 1927104..1928147 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ATCC 23235
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1922104..1933147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PQQ27_RS09585 (PQQ27_09585)	-	1922525..1923781 (-)	1257	WP_001795108.1	aminopeptidase	-
PQQ27_RS09590 (PQQ27_09590)	-	1923784..1923984 (-)	201	WP_000180460.1	DUF1128 family protein	-
PQQ27_RS09595 (PQQ27_09595)	-	1924131..1924595 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
PQQ27_RS09600 (PQQ27_09600)	-	1924602..1924877 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PQQ27_RS09605 (PQQ27_09605)	-	1925155..1926372 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
PQQ27_RS09610 (PQQ27_09610)	vraR	1926485..1927114 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PQQ27_RS09615 (PQQ27_09615)	vraS	1927104..1928147 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PQQ27_RS09620 (PQQ27_09620)	liaF	1928144..1928845 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PQQ27_RS09625 (PQQ27_09625)	-	1928860..1929246 (-)	387	WP_001110179.1	hypothetical protein	-
PQQ27_RS09630 (PQQ27_09630)	map	1929463..1930221 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PQQ27_RS09635 (PQQ27_09635)	-	1930752..1931738 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
PQQ27_RS09640 (PQQ27_09640)	-	1932169..1932582 (-)	414	WP_001557448.1	hypothetical protein	-
PQQ27_RS09645 (PQQ27_09645)	-	1932611..1932721 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=783030 PQQ27_RS09615 WP_001017131.1 1927104..1928147(-) (vraS) [Staphylococcus aureus strain ATCC 23235]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=783030 PQQ27_RS09615 WP_001017131.1 1927104..1928147(-) (vraS) [Staphylococcus aureus strain ATCC 23235]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1