Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   OTB22_RS09310 Genome accession   NZ_CP113267
Coordinates   1828417..1829241 (-) Length   274 a.a.
NCBI ID   WP_023396715.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1823417..1834241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS09305 (OTB22_09310) - 1826795..1828126 (-) 1332 WP_000390042.1 hemolysin family protein -
  OTB22_RS09310 (OTB22_09315) endA 1828417..1829241 (-) 825 WP_023396715.1 DNA-entry nuclease EndA Machinery gene
  OTB22_RS09315 (OTB22_09320) - 1829280..1829468 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  OTB22_RS09320 (OTB22_09325) murA 1829461..1830744 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  OTB22_RS09325 (OTB22_09330) - 1830768..1830998 (-) 231 WP_000250391.1 DUF1146 family protein -
  OTB22_RS09330 (OTB22_09335) sepM 1831056..1832093 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  OTB22_RS09335 (OTB22_09340) coaD 1832077..1832565 (-) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  OTB22_RS09340 (OTB22_09345) rsmD 1832555..1833094 (-) 540 WP_000691938.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  OTB22_RS09345 (OTB22_09350) asnA 1833159..1834151 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.62 Da        Isoelectric Point: 10.1197

>NTDB_id=761505 OTB22_RS09310 WP_023396715.1 1828417..1829241(-) (endA) [Streptococcus pneumoniae strain BC2]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=761505 OTB22_RS09310 WP_023396715.1 1828417..1829241(-) (endA) [Streptococcus pneumoniae strain BC2]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAATGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

97.81

100

0.978
  endA Streptococcus pneumoniae D39

97.81

100

0.978
  endA Streptococcus pneumoniae R6

97.81

100

0.978
  endA Streptococcus pneumoniae TIGR4

97.81

100

0.978