Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OS085_RS00910 Genome accession   NZ_CP113044
Coordinates   151337..152053 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain LeBlanc     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 146337..157053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS085_RS00880 - 146556..147182 (+) 627 WP_000522384.1 nitroreductase family protein -
  OS085_RS00885 - 147543..148328 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  OS085_RS14730 hld 148925..149005 (-) 81 WP_000046022.1 delta-hemolysin -
  OS085_RS00895 agrB 149295..149864 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  OS085_RS00900 agrD 149861..150001 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  OS085_RS00905 agrC 150026..151318 (+) 1293 WP_267836549.1 quorum-sensing sensor histidine kinase AgrC -
  OS085_RS00910 agrA 151337..152053 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OS085_RS00915 - 152125..152232 (+) 108 WP_001790167.1 hypothetical protein -
  OS085_RS00920 - 152420..153379 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  OS085_RS00925 - 153376..154860 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  OS085_RS00930 - 155009..155959 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=759440 OS085_RS00910 WP_000688492.1 151337..152053(+) (agrA) [Staphylococcus aureus strain LeBlanc]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=759440 OS085_RS00910 WP_000688492.1 151337..152053(+) (agrA) [Staphylococcus aureus strain LeBlanc]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1