Detailed information NTG0074865

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KUH140013_RS11350
• Genome accession: NZ_AP020324
• Coordinates: 2245596..2246483 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain KUN1163
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2240596..2251483

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KUH140013_RS11320 (KUN1163_2116)	-	2241328..2242089 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
KUH140013_RS11325 (KUN1163_2117)	-	2242334..2242789 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KUH140013_RS15390 (KUN1163_2118)	-	2242911..2243012 (+)	102	WP_000731976.1	SE2200 family small protein	-
KUH140013_RS11335 (KUN1163_2119)	-	2243072..2244496 (-)	1425	WP_000953755.1	alkaline phosphatase	-
KUH140013_RS11340 (KUN1163_2120)	-	2244694..2244894 (+)	201	WP_000604730.1	hypothetical protein	-
KUH140013_RS11345 (KUN1163_2121)	braR	2244920..2245585 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KUH140013_RS11350 (KUN1163_2122)	braS	2245596..2246483 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KUH140013_RS11355 (KUN1163_2123)	-	2246591..2247346 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KUH140013_RS11360 (KUN1163_2124)	-	2247343..2249343 (+)	2001	WP_000776751.1	ABC transporter permease	-
KUH140013_RS11365	-	2250002..2250115 (+)	114	Protein_2169	hypothetical protein	-
KUH140013_RS11375 (KUN1163_2125)	-	2250497..2250757 (+)	261	WP_001791974.1	hypothetical protein	-
KUH140013_RS11380 (KUN1163_2126)	-	2250767..2251264 (+)	498	WP_001065268.1	glutathione peroxidase	-
KUH140013_RS11385	-	2251372..2251464 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=74865 KUH140013_RS11350 WP_000143425.1 2245596..2246483(+) (braS) [Staphylococcus aureus strain KUN1163]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=74865 KUH140013_RS11350 WP_000143425.1 2245596..2246483(+) (braS) [Staphylococcus aureus strain KUN1163]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1