Detailed information NTG0737281

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: QA712_RS04575
• Genome accession: NZ_CP121539
• Coordinates: 809836..811206 (-)
• Length: 456 a.a.
• NCBI ID: WP_003130363.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain MA5
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 804836..816206

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA712_RS04560 (QA712_04540)	-	806007..807440 (-)	1434	WP_311803036.1	6-phospho-beta-glucosidase	-
QA712_RS04565 (QA712_04545)	yidD	807563..807829 (-)	267	WP_012898265.1	membrane protein insertion efficiency factor YidD	-
QA712_RS04570 (QA712_04550)	-	807946..809688 (-)	1743	WP_372757774.1	1-deoxy-D-xylulose-5-phosphate synthase	-
QA712_RS04575 (QA712_04555)	ciaH	809836..811206 (-)	1371	WP_003130363.1	cell wall metabolism sensor histidine kinase WalK	Regulator
QA712_RS04580 (QA712_04560)	ciaR	811299..811967 (-)	669	WP_021722129.1	response regulator transcription factor	Regulator
QA712_RS04585 (QA712_04565)	-	812145..813119 (-)	975	WP_372757776.1	LacI family DNA-binding transcriptional regulator	-
QA712_RS04590 (QA712_04570)	-	813272..815527 (-)	2256	WP_332529667.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 51300.85 Da
• Isoelectric Point: 9.4537

>NTDB_id=737281 QA712_RS04575 WP_003130363.1 809836..811206(-) (ciaH) [Lactococcus lactis strain MA5]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide

• Length: 1371 bp

>NTDB_id=737281 QA712_RS04575 WP_003130363.1 809836..811206(-) (ciaH) [Lactococcus lactis strain MA5]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAACTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAACTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACTGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACAATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGAGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGACAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (333-442)

• His Kinase A (phospho-acceptor) domain (HisKA) (223-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	48.837	94.298	0.461
ciaH	Streptococcus pneumoniae Rx1	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae D39	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae R6	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae TIGR4	44.321	98.465	0.436