Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P8R99_RS04675 Genome accession   NZ_CP121160
Coordinates   927028..927669 (-) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S5     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 922028..932669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS04650 - 922428..923411 (-) 984 WP_000764456.1 sugar-binding transcriptional regulator -
  P8R99_RS04655 - 923530..924285 (-) 756 WP_001080746.1 DeoR family transcriptional regulator -
  P8R99_RS04660 - 924406..925182 (+) 777 WP_000180537.1 glycyl-radical enzyme activating protein -
  P8R99_RS04665 - 925228..925584 (-) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  P8R99_RS04670 - 925586..926986 (-) 1401 WP_017647118.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  P8R99_RS04675 vraR 927028..927669 (-) 642 WP_000357891.1 response regulator transcription factor Regulator
  P8R99_RS04680 - 927662..928681 (-) 1020 WP_000716168.1 sensor histidine kinase -
  P8R99_RS04685 liaF 928678..929373 (-) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  P8R99_RS04690 pknB 929532..931487 (-) 1956 WP_000614565.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P8R99_RS04695 - 931487..932224 (-) 738 WP_000406234.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=736226 P8R99_RS04675 WP_000357891.1 927028..927669(-) (vraR) [Streptococcus agalactiae strain S5]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=736226 P8R99_RS04675 WP_000357891.1 927028..927669(-) (vraR) [Streptococcus agalactiae strain S5]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGATGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTATTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTAGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGACGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394