Detailed information NTG0720623

Bioinformatically predicted

Overview

• Name: lytF
• Type: Regulator
• Locus tag: PUW62_RS00270
• Genome accession: NZ_CP118046
• Coordinates: 40556..42490 (-)
• Length: 644 a.a.
• NCBI ID: WP_070241460.1
• Uniprot ID: A0A412PM75
• Organism: Streptococcus anginosus strain VSI52
• Function: cell lysis (predicted from homology) Cell lysis

Genomic Context

Location: 35556..47490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW62_RS00250 (PUW62_00250)	-	36889..37170 (+)	282	WP_024052903.1	hypothetical protein	-
PUW62_RS00255 (PUW62_00255)	purM	37130..38155 (+)	1026	WP_024052902.1	phosphoribosylformylglycinamidine cyclo-ligase	-
PUW62_RS00260 (PUW62_00260)	purN	38155..38709 (+)	555	WP_024052901.1	phosphoribosylglycinamide formyltransferase	-
PUW62_RS00265 (PUW62_00265)	purH	38950..40497 (+)	1548	WP_024052900.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-
PUW62_RS00270 (PUW62_00270)	lytF	40556..42490 (-)	1935	WP_070241460.1	GBS Bsp-like repeat-containing protein	Regulator
PUW62_RS00275 (PUW62_00275)	purD	42685..43950 (+)	1266	WP_024052898.1	phosphoribosylamine--glycine ligase	-
PUW62_RS00280 (PUW62_00280)	-	43940..44365 (+)	426	WP_024052897.1	DUF523 domain-containing protein	-
PUW62_RS00285 (PUW62_00285)	purE	44484..44972 (+)	489	WP_003037056.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
PUW62_RS00290 (PUW62_00290)	purK	44959..46047 (+)	1089	WP_024052896.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
PUW62_RS00295 (PUW62_00295)	-	46059..46283 (+)	225	WP_024052895.1	hypothetical protein	-
PUW62_RS00300 (PUW62_00300)	-	46297..46422 (+)	126	WP_257360479.1	hypothetical protein	-
PUW62_RS00305 (PUW62_00305)	-	46650..46793 (+)	144	WP_024052894.1	hypothetical protein	-

Sequence

Protein

• Length: 644 a.a.
• Molecular weight: 71121.90 Da
• Isoelectric Point: 8.6170

>NTDB_id=720623 PUW62_RS00270 WP_070241460.1 40556..42490(-) (lytF) [Streptococcus anginosus strain VSI52]
MKKYSQLFLLSNTILGVFSAQLTAQASEADNAQKSSNPAILASNITVNVSGNTASINYTRSQTQVPYTIYHAVWSDENGQ
DDIKWYSAPQTPTTAIDLRQHTGYGTFHVHTYININGKMVGLNGTTFKVEKPASGTVSTTVLGKTAQISFTRNKDQTNAN
ILHAVCSDEKGQDDIKWYTAGQDTTEIDLSNHKGYGVYHVHTYESKNGKMIGLNDTTFNLEKPNPSIQTSFPEPGIMDIQ
IKNVPKTIYKLTVPAWSDRNGQDDLQWYAATKNSDGSYNVRVELKKHNYDIGTYHIHLYGESYVKPEFTGLAGITAQVDA
DKLPSEEEQKPFFSVENINQEQGTYTVKVSETSKSKPIQSVRVPIWSTSNQSNIKWYAATNHGDGTFTTSFDIRNHQVFS
GTYTNHIYVKYKDGSEHSYATDSVAMSAEKIKTKVSVAKRSTYLYEVTVTDAYGDGKISLPTWSEVNGQDDIQWYTATKA
GNGIYKFTVDTQKHTGSGLFHTHVYRNLNGQIIGLTGTRYQVEKPAISFQPNYAAATTYPKGQCTWGAKALAPWAGNYWG
NGGDWAASARRAGFKTGTAPQVGAIICWTDGGYGHVGVVTHVASNTRIQIQEANYAGKQYIGNFRGWFNPHAAGQGAVSY
IYPK

Nucleotide

• Length: 1935 bp

>NTDB_id=720623 PUW62_RS00270 WP_070241460.1 40556..42490(-) (lytF) [Streptococcus anginosus strain VSI52]
ATGAAGAAATACAGTCAATTATTTTTACTATCTAACACTATTTTGGGCGTTTTTTCTGCTCAACTAACTGCTCAAGCCTC
GGAAGCAGATAATGCTCAAAAAAGCTCAAATCCAGCAATTCTTGCTAGCAACATTACCGTCAATGTTTCTGGAAATACAG
CTTCTATTAACTACACACGCTCACAGACACAAGTTCCTTACACCATTTACCACGCTGTTTGGTCTGATGAAAATGGGCAA
GACGATATCAAATGGTATTCTGCGCCTCAGACACCCACTACAGCTATTGATTTGCGTCAGCACACTGGTTATGGAACCTT
TCATGTTCACACTTATATCAATATCAATGGAAAAATGGTTGGTTTAAACGGAACGACTTTCAAAGTAGAAAAACCAGCTA
GCGGCACGGTTTCTACAACCGTTTTAGGAAAGACTGCTCAAATATCCTTTACTCGAAACAAAGATCAAACAAATGCCAAT
ATTTTACACGCTGTTTGCTCTGACGAAAAAGGACAAGATGACATCAAGTGGTATACGGCAGGGCAAGACACAACAGAAAT
TGACTTATCCAATCATAAAGGATACGGTGTTTACCATGTTCATACTTATGAAAGTAAAAACGGAAAGATGATTGGATTAA
ATGACACCACTTTTAACCTTGAAAAACCAAATCCTTCTATCCAGACTAGCTTTCCTGAGCCTGGTATCATGGATATTCAG
ATCAAAAATGTTCCTAAAACAATCTACAAACTAACGGTTCCGGCTTGGTCTGACCGCAACGGACAGGATGATCTTCAATG
GTATGCAGCTACTAAAAATTCTGATGGAAGCTACAATGTTAGAGTTGAGCTAAAAAAACACAACTATGACATAGGAACTT
ATCATATTCATCTTTACGGAGAAAGCTATGTCAAACCAGAGTTTACTGGCTTAGCTGGAATCACTGCCCAAGTTGATGCT
GATAAATTGCCTTCTGAAGAAGAGCAAAAACCATTCTTCTCTGTTGAAAATATCAATCAAGAACAAGGGACTTATACCGT
CAAAGTTAGTGAAACTTCAAAGTCCAAGCCGATTCAATCCGTCCGAGTACCTATTTGGAGCACGAGCAATCAAAGCAATA
TCAAGTGGTATGCAGCCACTAATCACGGTGATGGAACCTTTACGACAAGCTTTGATATTCGCAATCATCAAGTTTTTTCC
GGAACATACACCAATCATATTTATGTGAAATATAAAGACGGTAGCGAGCATAGTTATGCAACGGATTCGGTTGCTATGTC
CGCAGAAAAAATTAAAACCAAAGTATCTGTCGCTAAACGCTCAACTTATCTTTATGAGGTGACGGTGACAGATGCTTACG
GCGATGGCAAGATTAGCCTACCGACTTGGTCTGAAGTCAACGGCCAAGATGATATTCAGTGGTACACCGCTACTAAAGCT
GGAAATGGAATTTACAAATTCACAGTTGATACGCAAAAACACACTGGCAGTGGCCTTTTCCATACACATGTTTACCGCAA
TCTCAACGGTCAAATAATTGGACTAACAGGTACGAGATATCAAGTAGAGAAGCCTGCTATCTCTTTCCAACCAAATTATG
CCGCAGCAACGACTTATCCAAAAGGGCAATGCACTTGGGGCGCCAAAGCTCTTGCACCTTGGGCTGGCAATTACTGGGGC
AATGGTGGTGATTGGGCTGCTAGCGCCAGACGAGCTGGTTTTAAAACCGGTACAGCTCCACAAGTAGGGGCTATTATTTG
TTGGACAGACGGTGGTTACGGTCACGTTGGAGTTGTTACTCACGTTGCCTCAAACACACGCATTCAGATTCAAGAGGCCA
ACTACGCTGGAAAACAGTATATTGGCAACTTCCGCGGCTGGTTCAATCCTCATGCAGCTGGACAAGGAGCAGTTAGTTAC
ATTTATCCAAAATAA

Domains

Predicted by InterProScan.

• CHAP domain (CHAP) (537-614)

• GBS Bsp-like repeat (GBS_Bsp-like) (232-302)

• GBS Bsp-like repeat (GBS_Bsp-like) (158-218)

• GBS Bsp-like repeat (GBS_Bsp-like) (335-421)

• GBS Bsp-like repeat (GBS_Bsp-like) (67-126)

• GBS Bsp-like repeat (GBS_Bsp-like) (437-510)

3D structure

• AlphaFold DB: A0A412PM75

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lytF	Streptococcus gordonii strain NCTC7865	45.402	81.056	0.368
lytF	Streptococcus gordonii str. Challis substr. CH1	44.444	81.056	0.36