Detailed information NTG0711090

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: POF62_RS00405
• Genome accession: NZ_CP116707
• Coordinates: 63833..64741 (+)
• Length: 302 a.a.
• NCBI ID: WP_000912095.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain A909 sCas9revertant
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 58833..69741

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
POF62_RS00385 (POF62_00385)	purE	59350..59838 (+)	489	WP_001182531.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
POF62_RS00390 (POF62_00390)	purK	59825..60916 (+)	1092	WP_001084008.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
POF62_RS00395 (POF62_00395)	-	60969..62360 (+)	1392	WP_001079797.1	hypothetical protein	-
POF62_RS00400 (POF62_00400)	purB	62382..63680 (+)	1299	WP_000572890.1	adenylosuccinate lyase	-
POF62_RS00405 (POF62_00405)	comR	63833..64741 (+)	909	WP_000912095.1	XRE family transcriptional regulator	Regulator
POF62_RS00410 (POF62_00410)	ruvB	64942..65940 (+)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
POF62_RS00415 (POF62_00415)	-	66092..66529 (+)	438	WP_000754818.1	low molecular weight protein-tyrosine-phosphatase	-
POF62_RS00420 (POF62_00420)	-	66536..66916 (+)	381	WP_000787702.1	membrane protein	-
POF62_RS00425 (POF62_00425)	-	66913..68691 (+)	1779	WP_001220907.1	acyltransferase family protein	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35727.11 Da
• Isoelectric Point: 5.5329

>NTDB_id=711090 POF62_RS00405 WP_000912095.1 63833..64741(+) (comR) [Streptococcus agalactiae strain A909 sCas9revertant]
MLKHFGSKVRKFRESQQVTREEFCGDESELSVRQLARIEAGESVPNLSKAHYIARNLGVSLDSLTAGASLELSKKYKELK
YLILRTPTYNDTDRLDLIEKYLDEIYLNFYDDLPEDEKIAIESIQSSLDIYISKSHHFGDDLIREYMNQIKRKKIYSIND
LLIIKLWQYKITASRYDPNIFKIDTFIGTIDKLLNQVKVLSIENLFLLRDVLIYSLGILFILAEYQQIENIINTLNDILI
KTQDFQKRPIIDMFEWKYQLFYKENREVAKRKYQESTLFAQLIGDQVLVTQLKEEWKADYIE

Nucleotide

• Length: 909 bp

>NTDB_id=711090 POF62_RS00405 WP_000912095.1 63833..64741(+) (comR) [Streptococcus agalactiae strain A909 sCas9revertant]
ATGTTAAAACATTTTGGTAGTAAAGTAAGGAAGTTTAGGGAATCTCAACAGGTGACACGAGAAGAATTTTGTGGCGATGA
ATCAGAGTTATCGGTCCGACAGCTGGCTCGGATTGAAGCAGGAGAATCTGTTCCAAATTTATCTAAGGCGCATTATATCG
CTAGAAATCTAGGAGTTAGTTTAGATTCCTTAACAGCAGGAGCGAGTTTAGAACTGTCAAAAAAATATAAGGAATTAAAG
TATCTTATATTAAGGACGCCTACCTACAATGATACAGATAGACTTGATTTGATTGAAAAATATCTAGATGAGATTTATTT
AAATTTCTATGATGATTTACCTGAAGATGAAAAAATAGCAATTGAGTCCATACAAAGTTCTTTAGATATTTATATTTCTA
AAAGCCATCATTTTGGAGATGACCTGATTAGGGAATACATGAATCAAATTAAACGAAAAAAGATTTACTCTATCAATGAC
TTACTTATAATTAAACTATGGCAATATAAGATTACTGCTAGCAGGTATGATCCCAATATTTTTAAAATAGATACATTTAT
TGGTACTATAGATAAGTTGCTTAATCAAGTAAAGGTATTATCAATTGAAAACCTGTTTTTATTAAGGGATGTCCTCATTT
ATTCGTTAGGTATATTGTTTATATTAGCTGAATATCAGCAAATAGAAAATATAATAAATACTCTAAATGATATTTTAATA
AAAACTCAGGATTTTCAAAAGAGGCCAATAATAGATATGTTCGAATGGAAATATCAGTTGTTTTATAAAGAAAATAGGGA
AGTGGCTAAAAGAAAGTATCAGGAATCAACTCTTTTTGCTCAATTAATTGGCGATCAAGTTTTAGTTACACAGCTAAAAG
AGGAATGGAAAGCAGACTATATAGAATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (74-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	45.151	99.007	0.447
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.296	95.033	0.43
comR	Streptococcus pyogenes MGAS315	43.478	99.007	0.43
comR	Streptococcus pyogenes MGAS8232	41.914	100	0.421
comR	Streptococcus suis P1/7	42.424	98.344	0.417
comR	Streptococcus suis 05ZYH33	42.424	98.344	0.417
comR	Streptococcus suis D9	38.384	98.344	0.377