Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J58_RS03615 Genome accession   NZ_AP018772
Coordinates   711509..712726 (+) Length   405 a.a.
NCBI ID   WP_005686722.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-1 isolate 15H02     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 706509..717726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J58_RS03595 (CHBNIII1_06960) corC 707474..708373 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J58_RS03600 (CHBNIII1_06970) ampD 708994..709554 (-) 561 WP_005686728.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J58_RS03605 (CHBNIII1_06980) pilA 709669..710118 (+) 450 WP_005686726.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J58_RS03610 (CHBNIII1_06990) pilB 710115..711512 (+) 1398 WP_005686724.1 GspE/PulE family protein Machinery gene
  K6J58_RS03615 (CHBNIII1_07000) pilC 711509..712726 (+) 1218 WP_005686722.1 type II secretion system F family protein Machinery gene
  K6J58_RS03620 (CHBNIII1_07010) pilD 712723..713415 (+) 693 WP_105887051.1 A24 family peptidase Machinery gene
  K6J58_RS03625 (CHBNIII1_07020) rho 713469..714731 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J58_RS03630 (CHBNIII1_07030) metJ 714979..715296 (+) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  K6J58_RS03635 (CHBNIII1_07040) cueR 715310..715696 (-) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  K6J58_RS03640 (CHBNIII1_07050) - 715773..715979 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  K6J58_RS03645 (CHBNIII1_07060) - 716064..716270 (+) 207 WP_105887050.1 heavy-metal-associated domain-containing protein -
  K6J58_RS03650 - 716245..716330 (+) 86 Protein_711 heavy metal-associated domain-containing protein -
  K6J58_RS03655 (CHBNIII1_07070) - 716355..716561 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J58_RS03660 (CHBNIII1_07080) - 716635..716841 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46122.32 Da        Isoelectric Point: 9.7232

>NTDB_id=71008 K6J58_RS03615 WP_005686722.1 711509..712726(+) (pilC) [Haemophilus influenzae strain CHBN-III-1 isolate 15H02]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRELTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQKKNQLISVTPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=71008 K6J58_RS03615 WP_005686722.1 711509..712726(+) (pilC) [Haemophilus influenzae strain CHBN-III-1 isolate 15H02]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGAGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAAAAGAAAAATCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAGGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.975
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment