Detailed information NTG0709837

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: PFZ59_RS02405
• Genome accession: NZ_CP116393
• Coordinates: 472941..473843 (-)
• Length: 300 a.a.
• NCBI ID: WP_208582736.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SS/UPM/MY/F001
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 467941..478843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PFZ59_RS02385 (PFZ59_02385)	-	468021..469544 (-)	1524	WP_277697414.1	quinol oxidase	-
PFZ59_RS02390 (PFZ59_02390)	-	469735..470955 (-)	1221	WP_277697415.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
PFZ59_RS02395 (PFZ59_02395)	-	471161..471307 (-)	147	WP_208582737.1	hypothetical protein	-
PFZ59_RS02400 (PFZ59_02400)	-	471469..472725 (+)	1257	WP_277697764.1	ISL3 family transposase	-
PFZ59_RS02405 (PFZ59_02405)	comR	472941..473843 (-)	903	WP_208582736.1	helix-turn-helix domain-containing protein	Regulator
PFZ59_RS02410 (PFZ59_02410)	-	473916..474539 (-)	624	WP_063076929.1	HAD-IA family hydrolase	-
PFZ59_RS02415 (PFZ59_02415)	-	474541..475287 (-)	747	WP_277697416.1	GNAT family N-acetyltransferase	-
PFZ59_RS02420 (PFZ59_02420)	ruvB	475287..476288 (-)	1002	WP_014735241.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
PFZ59_RS02425 (PFZ59_02425)	-	476416..477075 (+)	660	WP_208582472.1	amino acid ABC transporter permease	-
PFZ59_RS02430 (PFZ59_02430)	-	477056..477733 (+)	678	Protein_445	amino acid ABC transporter permease	-
PFZ59_RS02435 (PFZ59_02435)	-	477738..478484 (+)	747	WP_277697417.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35322.38 Da
• Isoelectric Point: 4.4250

>NTDB_id=709837 PFZ59_RS02405 WP_208582736.1 472941..473843(-) (comR) [Streptococcus suis strain SS/UPM/MY/F001]
MNDKEFGQRVRQLRENASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMGKRADMMTEIYDDYYDDLPEEEKIAIDAIQSTIDVFETKTAEFGQDILEDYFEQIHRKKQFSVND
LLIIQLYLINLRMEVKQSSDFQYFLELVEKFPSQVELVESGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAATALYEEALLFARIIGNAHLTAKLEEEWRKDSQL

Nucleotide

• Length: 903 bp

>NTDB_id=709837 PFZ59_RS02405 WP_208582736.1 472941..473843(-) (comR) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAAACGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAA
TTTGATGTGCTTCGCACACCAACTTATGAAAATGAGGAATTGATGGGAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCCGAGGAGGAGAAAATAGCAATCGATGCTATTCAATCAACCATTGACGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAGATACATAGAAAAAAACAATTTTCAGTCAATGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGTAGTGATTTCCAGTATTTTTTAGAGTT
GGTTGAAAAGTTTCCGAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACT
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCAGC
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCACACCTAACGGCTAAATTAGAAGAAGAGT
GGAGAAAAGATAGTCAATTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix domain (HTH_31) (5-60)

• ComR tetratricopeptide (ComR_TPR) (73-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	66.89	99.667	0.667
comR	Streptococcus suis 05ZYH33	66.89	99.667	0.667
comR	Streptococcus suis D9	60.465	100	0.607
comR	Streptococcus mutans UA159	43.478	99.667	0.433
comR	Streptococcus pyogenes MGAS8232	40.203	98.667	0.397
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	40.345	96.667	0.39
comR	Streptococcus pyogenes MGAS315	36.242	99.333	0.36