Detailed information NTG0709544

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: PGH47_RS24145
• Genome accession: NZ_CP116353
• Coordinates: 5404141..5405265 (-)
• Length: 374 a.a.
• NCBI ID: WP_030958303.1
• Uniprot ID: A0A7H8T8E1
• Organism: Streptomyces sp. HUAS 31
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5399141..5410265

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PGH47_RS24120 (PGH47_24120)	-	5399632..5400222 (-)	591	WP_271668137.1	hypothetical protein	-
PGH47_RS24125 (PGH47_24125)	-	5400381..5400920 (-)	540	WP_030961701.1	SigE family RNA polymerase sigma factor	-
PGH47_RS24130 (PGH47_24130)	-	5401234..5402172 (-)	939	WP_271665178.1	A/G-specific adenine glycosylase	-
PGH47_RS24135 (PGH47_24135)	-	5402366..5402728 (+)	363	WP_271665179.1	hypothetical protein	-
PGH47_RS24140 (PGH47_24140)	-	5403121..5403954 (+)	834	WP_271665180.1	hypothetical protein	-
PGH47_RS24145 (PGH47_24145)	disA	5404141..5405265 (-)	1125	WP_030958303.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
PGH47_RS24150 (PGH47_24150)	radA/sms	5405346..5406755 (-)	1410	WP_271665181.1	DNA repair protein RadA	Machinery gene
PGH47_RS24155 (PGH47_24155)	-	5406971..5408767 (+)	1797	WP_271665182.1	hypothetical protein	-
PGH47_RS24160 (PGH47_24160)	-	5408806..5409666 (-)	861	WP_271665183.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40110.79 Da
• Isoelectric Point: 4.9201

>NTDB_id=709544 PGH47_RS24145 WP_030958303.1 5404141..5405265(-) (disA) [Streptomyces sp. HUAS 31]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGFDKTVESMSTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQFVPDATIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALYELDALTHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=709544 PGH47_RS24145 WP_030958303.1 5404141..5405265(-) (disA) [Streptomyces sp. HUAS 31]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGCGGGAGTTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCGGTGGCTCCCGGCACCGCCTTGCGCGACGGGCTCGAACGCGTCCTGCGCGGCAACACCGGCGGACTCATCGTGC
TCGGCTTCGACAAGACCGTCGAGTCGATGAGCACGGGTGGATTCGTCCTGGATGTCGAGTTCACGGCTACGCGACTGCGT
GAGCTGTGCAAGCTCGACGGCGGCATCGTCCTGTCGTCCGACCTGTCGAAGATCCTTCGCGCGGGTGTGCAGTTCGTGCC
GGACGCGACGATCCCCACGGAGGAGACCGGAACCCGGCACCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTCTACGTCGACGGCCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCTCGGCGGTGGCGCAGCGCCTGGAGATGGTCCGGCGCATCG
CGACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGTCTTCTCGCCCTCCAGCTGGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGCGAGCTCGTGGTGCGCGACTACGTCCCCGAGCCGACGGCCAAGCGCTCCCGCACGGTCGACGA
GGCGCTGTACGAACTGGACGCGCTCACCCACGCCGAGCTGCTCGAACTGCCCACGGTGGCACGGGCGTTGGGCTACACCG
GCTCTCCGGAGGCGCTGGACTCGGCGGTCTCTCCGCGCGGCTTCCGTCTGCTGGCCAAGGTGCCCAGGCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTGCTCGCCGCCAGCGTGGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGGGCACGCAGCGTCCGCGAGGGCCTGTCGCGGCTGGCGGAGAGCTCGATCCTGGAACGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0A7H8T8E1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441