Detailed information NTG0705380

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NLY78_RS07680
• Genome accession: NZ_CP100435
• Coordinates: 1555101..1556150 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain DE609B
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1550101..1561150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY78_RS07660 (NLY78_07655)	nadE	1550507..1551331 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NLY78_RS07665 (NLY78_07660)	-	1552627..1553154 (-)	528	WP_012027591.1	VanZ family protein	-
NLY78_RS07670 (NLY78_07665)	rlmN	1553151..1554263 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NLY78_RS07675 (NLY78_07670)	-	1554272..1554913 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
NLY78_RS07680 (NLY78_07675)	sepM	1555101..1556150 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NLY78_RS07685 (NLY78_07680)	coaD	1556137..1556625 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
NLY78_RS07690 (NLY78_07685)	rsmD	1556615..1557154 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NLY78_RS07695 (NLY78_07690)	-	1557462..1558184 (-)	723	WP_012027598.1	lipoprotein	-
NLY78_RS07700 (NLY78_07695)	-	1558241..1558627 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NLY78_RS07705 (NLY78_07700)	-	1558627..1558845 (-)	219	WP_004194736.1	YqgQ family protein	-
NLY78_RS07710 (NLY78_07705)	-	1559153..1559755 (-)	603	WP_012027601.1	response regulator transcription factor	-
NLY78_RS07715 (NLY78_07710)	-	1559752..1560846 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=705380 NLY78_RS07680 WP_012775295.1 1555101..1556150(-) (sepM) [Streptococcus suis strain DE609B]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=705380 NLY78_RS07680 WP_012775295.1 1555101..1556150(-) (sepM) [Streptococcus suis strain DE609B]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605