Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | NDQ69_RS02340 | Genome accession | NZ_CP098548 |
| Coordinates | 453359..453970 (+) | Length | 203 a.a. |
| NCBI ID | WP_033911077.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 9343 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 444290..492790 | 453359..453970 | within | 0 |
Gene organization within MGE regions
Location: 444290..492790
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NDQ69_RS02290 (NDQ69_02275) | - | 444290..445366 (-) | 1077 | WP_229931480.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| NDQ69_RS02295 (NDQ69_02280) | cysW | 445363..446223 (-) | 861 | WP_003699617.1 | sulfate ABC transporter permease subunit CysW | - |
| NDQ69_RS02300 (NDQ69_02285) | cysT | 446412..447239 (-) | 828 | WP_003699619.1 | sulfate ABC transporter permease subunit CysT | - |
| NDQ69_RS02305 (NDQ69_02290) | - | 447420..447752 (+) | 333 | WP_003687908.1 | hypothetical protein | - |
| NDQ69_RS02310 (NDQ69_02295) | - | 448079..448588 (+) | 510 | WP_003687909.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| NDQ69_RS02315 (NDQ69_02300) | - | 448820..449401 (-) | 582 | WP_003690895.1 | superoxide dismutase | - |
| NDQ69_RS02320 (NDQ69_02305) | dnaB | 449565..450971 (+) | 1407 | WP_003699622.1 | replicative DNA helicase | - |
| NDQ69_RS02325 (NDQ69_02310) | pilH | 451125..451790 (+) | 666 | WP_229931479.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| NDQ69_RS02330 (NDQ69_02315) | pilV | 451822..452433 (+) | 612 | WP_003699626.1 | type IV pilus modification protein PilV | Machinery gene |
| NDQ69_RS02335 (NDQ69_02320) | pilJ | 452430..453380 (+) | 951 | WP_003699627.1 | PilW family protein | Machinery gene |
| NDQ69_RS02340 (NDQ69_02325) | pilK | 453359..453970 (+) | 612 | WP_033911077.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| NDQ69_RS02345 (NDQ69_02330) | pilL | 453972..454445 (+) | 474 | WP_172760650.1 | PilX family type IV pilin | Machinery gene |
| NDQ69_RS02350 (NDQ69_02335) | - | 454515..454823 (-) | 309 | WP_025456177.1 | AzlD family protein | - |
| NDQ69_RS02355 (NDQ69_02340) | - | 454820..455530 (-) | 711 | Protein_462 | AzlC family ABC transporter permease | - |
| NDQ69_RS02360 (NDQ69_02345) | dut | 455696..456148 (+) | 453 | WP_003699637.1 | dUTP diphosphatase | - |
| NDQ69_RS02365 (NDQ69_02350) | dapC | 456224..457411 (+) | 1188 | WP_003699639.1 | succinyldiaminopimelate transaminase | - |
| NDQ69_RS02370 (NDQ69_02355) | yaaA | 457567..458346 (+) | 780 | WP_003699641.1 | peroxide stress protein YaaA | - |
| NDQ69_RS02385 (NDQ69_02370) | - | 458876..460069 (+) | 1194 | WP_017146746.1 | phage integrase central domain-containing protein | - |
| NDQ69_RS02390 (NDQ69_02375) | - | 460425..460694 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| NDQ69_RS02395 (NDQ69_02380) | - | 460889..461572 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| NDQ69_RS11770 | - | 461853..462119 (-) | 267 | Protein_469 | hypothetical protein | - |
| NDQ69_RS02405 (NDQ69_02390) | - | 462230..462445 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NDQ69_RS02410 (NDQ69_02395) | - | 462497..462988 (-) | 492 | WP_033911206.1 | siphovirus Gp157 family protein | - |
| NDQ69_RS02415 (NDQ69_02400) | - | 462985..463167 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NDQ69_RS02420 (NDQ69_02405) | - | 463307..463993 (-) | 687 | WP_010357532.1 | phage replication initiation protein, NGO0469 family | - |
| NDQ69_RS02425 (NDQ69_02410) | - | 464062..464223 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| NDQ69_RS02430 (NDQ69_02415) | - | 464220..464495 (-) | 276 | WP_033911205.1 | NGO1622 family putative holin | - |
| NDQ69_RS02435 (NDQ69_02420) | - | 464648..464980 (-) | 333 | WP_003695500.1 | hypothetical protein | - |
| NDQ69_RS02440 (NDQ69_02425) | - | 465122..465415 (-) | 294 | WP_229931463.1 | hypothetical protein | - |
| NDQ69_RS02445 (NDQ69_02430) | - | 465412..465888 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| NDQ69_RS02450 (NDQ69_02435) | - | 465921..466121 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| NDQ69_RS02455 (NDQ69_02440) | - | 466605..466823 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| NDQ69_RS02460 (NDQ69_02445) | - | 466840..467199 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| NDQ69_RS02465 (NDQ69_02450) | - | 467200..467739 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| NDQ69_RS02470 (NDQ69_02455) | - | 467899..468615 (-) | 717 | WP_003695999.1 | helix-turn-helix transcriptional regulator | - |
| NDQ69_RS02475 (NDQ69_02460) | - | 468996..469223 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NDQ69_RS02480 (NDQ69_02465) | - | 469341..469808 (+) | 468 | WP_229692802.1 | hypothetical protein | - |
| NDQ69_RS02485 (NDQ69_02470) | - | 469903..470406 (+) | 504 | WP_010360005.1 | hypothetical protein | - |
| NDQ69_RS02490 (NDQ69_02475) | - | 470403..471764 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NDQ69_RS02495 (NDQ69_02480) | - | 471781..472011 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| NDQ69_RS02500 (NDQ69_02485) | - | 472103..472597 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| NDQ69_RS02505 (NDQ69_02490) | - | 472792..472941 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| NDQ69_RS02510 (NDQ69_02495) | - | 472969..473250 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NDQ69_RS02515 (NDQ69_02500) | - | 473241..473678 (+) | 438 | WP_229433529.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NDQ69_RS02520 (NDQ69_02505) | - | 473671..473976 (+) | 306 | WP_025456182.1 | DUF1364 domain-containing protein | - |
| NDQ69_RS02525 (NDQ69_02510) | - | 473973..474356 (+) | 384 | WP_003699764.1 | recombination protein NinB | - |
| NDQ69_RS02530 (NDQ69_02515) | - | 474347..474865 (+) | 519 | WP_003693459.1 | HNH endonuclease | - |
| NDQ69_RS02535 (NDQ69_02520) | - | 474930..475352 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| NDQ69_RS02540 (NDQ69_02525) | - | 475352..475891 (+) | 540 | WP_003693457.1 | hypothetical protein | - |
| NDQ69_RS02545 (NDQ69_02530) | - | 475872..477146 (+) | 1275 | WP_309491694.1 | PBSX family phage terminase large subunit | - |
| NDQ69_RS02550 (NDQ69_02535) | - | 477131..479398 (+) | 2268 | WP_229433533.1 | hypothetical protein | - |
| NDQ69_RS02555 (NDQ69_02540) | - | 479618..480832 (+) | 1215 | WP_017146865.1 | hypothetical protein | - |
| NDQ69_RS02560 (NDQ69_02545) | - | 480829..488136 (+) | 7308 | WP_229931478.1 | PLxRFG domain-containing protein | - |
| NDQ69_RS02565 (NDQ69_02550) | - | 488762..490057 (+) | 1296 | WP_003693441.1 | DUF4043 family protein | - |
| NDQ69_RS02570 (NDQ69_02555) | - | 490115..490588 (+) | 474 | WP_003693439.1 | hypothetical protein | - |
| NDQ69_RS02575 (NDQ69_02560) | - | 490594..491079 (+) | 486 | WP_003693438.1 | hypothetical protein | - |
| NDQ69_RS02580 (NDQ69_02565) | - | 491076..491750 (+) | 675 | WP_003693436.1 | hypothetical protein | - |
| NDQ69_RS02585 (NDQ69_02570) | - | 491753..491902 (+) | 150 | WP_017146863.1 | hypothetical protein | - |
| NDQ69_RS02590 (NDQ69_02575) | - | 491939..492790 (-) | 852 | WP_003699775.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 203 a.a. Molecular weight: 22068.97 Da Isoelectric Point: 7.5813
>NTDB_id=696964 NDQ69_RS02340 WP_033911077.1 453359..453970(+) (pilK) [Neisseria gonorrhoeae strain 9343]
MRKQNALTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCEKGLCTAVNVRTNNNGNEEAFGNIVVQGKPTVEAVKRSCPAKSGKNSTGLCIDNQGVEYEKGTASVSKMP
RYIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
MRKQNALTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCEKGLCTAVNVRTNNNGNEEAFGNIVVQGKPTVEAVKRSCPAKSGKNSTGLCIDNQGVEYEKGTASVSKMP
RYIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
Nucleotide
Download Length: 612 bp
>NTDB_id=696964 NDQ69_RS02340 WP_033911077.1 453359..453970(+) (pilK) [Neisseria gonorrhoeae strain 9343]
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAAAGGTCTGTGTACCGCAGTGAATGTGCGGACAAATAATAATGGTAA
TGAAGAGGCTTTTGGCAATATCGTGGTGCAAGGCAAGCCTACCGTTGAGGCGGTGAAGCGTTCTTGCCCTGCAAAGTCTG
GCAAAAATTCTACCGGCCTGTGCATTGACAATCAGGGAGTGGAATATGAGAAAGGCACGGCAAGCGTCAGCAAAATGCCG
CGCTATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGC
CAATACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAAAGGTCTGTGTACCGCAGTGAATGTGCGGACAAATAATAATGGTAA
TGAAGAGGCTTTTGGCAATATCGTGGTGCAAGGCAAGCCTACCGTTGAGGCGGTGAAGCGTTCTTGCCCTGCAAAGTCTG
GCAAAAATTCTACCGGCCTGTGCATTGACAATCAGGGAGTGGAATATGAGAAAGGCACGGCAAGCGTCAGCAAAATGCCG
CGCTATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGC
CAATACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
95.567 |
100 |
0.956 |