Detailed information NTG0692159

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: N6H00_RS22140
• Genome accession: NZ_CP114036
• Coordinates: 5228001..5229059 (-)
• Length: 352 a.a.
• NCBI ID: WP_268977070.1
• Uniprot ID: A0ABY9V9R6
• Organism: Streptomyces sp. S465
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5223001..5234059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N6H00_RS22115 (N6H00_22115)	cseB	5223413..5224120 (-)	708	WP_268973554.1	two-component system response regulator CseB	-
N6H00_RS22120 (N6H00_22120)	-	5224130..5224855 (-)	726	WP_268973555.1	hypothetical protein	-
N6H00_RS22125 (N6H00_22125)	-	5224843..5225454 (-)	612	WP_268973556.1	SigE family RNA polymerase sigma factor	-
N6H00_RS22130 (N6H00_22130)	-	5225745..5226671 (-)	927	WP_268973558.1	A/G-specific adenine glycosylase	-
N6H00_RS22135 (N6H00_22135)	-	5226922..5227785 (+)	864	WP_268973559.1	hypothetical protein	-
N6H00_RS22140 (N6H00_22140)	disA	5228001..5229059 (-)	1059	WP_268977070.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
N6H00_RS22145 (N6H00_22145)	radA/sms	5229816..5231240 (-)	1425	WP_268973560.1	DNA repair protein RadA	Machinery gene
N6H00_RS22150 (N6H00_22150)	-	5231451..5233145 (+)	1695	WP_268973561.1	sigma-70 family RNA polymerase sigma factor	-
N6H00_RS22155 (N6H00_22155)	-	5233209..5234051 (-)	843	WP_268977071.1	hypothetical protein	-

Sequence

Protein

• Length: 352 a.a.
• Molecular weight: 38161.90 Da
• Isoelectric Point: 5.0869

>NTDB_id=692159 N6H00_RS22140 WP_268977070.1 5228001..5229059(-) (disA) [Streptomyces sp. S465]
MRASLSAVAPGTALRDGLERVLRGNTGGLIVLGTDKTVESLCTGGFVIDVEFTATRLRELCKLDGALVLDKDITKIVRAG
VQLVPDAAIPTEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVEPERELVARDYVPEPTAKRT
RTVADALAELDRLTHAELLELPIVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGAIIERLVEHFGGLQKLLAASVDD
LQMVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1059 bp

>NTDB_id=692159 N6H00_RS22140 WP_268977070.1 5228001..5229059(-) (disA) [Streptomyces sp. S465]
ATGCGTGCCTCCCTGAGCGCGGTCGCGCCCGGCACGGCCCTGCGCGACGGCCTTGAGCGCGTCCTCCGGGGAAACACCGG
CGGCCTGATCGTGCTCGGCACCGACAAGACCGTCGAGTCGCTGTGTACCGGCGGCTTCGTCATCGACGTCGAGTTCACCG
CGACCCGGCTGCGCGAGCTGTGCAAGCTTGACGGCGCGCTGGTCCTCGACAAGGACATCACCAAGATCGTGCGGGCCGGG
GTGCAGCTGGTCCCCGACGCGGCGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCGCAGCGCGTCTCCATCCA
GACCGGGTTCCCGGTGGTCTCCGTCAGCCAGTCGATGCGGCTGATCGCGCTGTACGTCGACGGTCAGCGGCGGGTCCTGG
AGGATTCGGCGGCGATCCTCTCCCGTGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTC
GCGGGCACGCTCTCGGCCCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGAGCGCGGTCGCGCAGCGGCTGGAGAT
GGTCCGGCGCATCGCCACCGAGATCGCGGAGTACGTGGTCGAGCTGGGCACGGACGGCCGGCTGCTCTCCCTCCAGCTGG
ACGAGCTGATCGCGGGCGTCGAGCCGGAGCGTGAGCTGGTGGCGCGCGACTACGTCCCCGAGCCGACCGCCAAGCGCACT
CGCACGGTGGCCGACGCGCTCGCCGAGCTGGACCGGCTGACCCACGCCGAGCTGCTCGAACTGCCCATCGTGGCCCGTGC
GCTGGGCTACACCGGCTCGCCCGAGACCCTCGACTCGGCGGTTTCGCCGCGTGGCTTCCGGCTGCTGGCCAAGGTGCCGC
GGCTTCCGGGCGCCATCATCGAGCGGCTGGTGGAGCACTTCGGTGGCCTGCAGAAGCTGCTGGCGGCGAGCGTGGACGAT
CTCCAGATGGTGGACGGCGTGGGCGAGGCGCGGGCGCGCTCGGTCCGCGAGGGCCTGTCGCGGCTTGCCGAGTCGTCCAT
CCTGGAGCGGTACGTCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (16-129)

• Helix-hairpin-helix motif (HHH_2) (302-337)

• DisA bacterial checkpoint controller linker region (DisA-linker) (133-275)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	47.11	98.295	0.463