Detailed information NTG0690728

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M8970_RS12355
• Genome accession: NZ_CP097590
• Coordinates: 2528705..2529868 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UA0195
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2523705..2534868

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8970_RS12325	-	2523969..2524388 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
M8970_RS12330	comFC	2524462..2525151 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
M8970_RS12335	-	2525157..2525441 (-)	285	WP_003151389.1	competence protein ComFB	-
M8970_RS12340	comFA	2525499..2526884 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
M8970_RS12345	-	2526993..2527841 (-)	849	WP_032876160.1	DegV family protein	-
M8970_RS12350	degU	2527939..2528628 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M8970_RS12355	degS	2528705..2529868 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M8970_RS12360	-	2530091..2530738 (+)	648	WP_007614107.1	YigZ family protein	-
M8970_RS12365	-	2530743..2531924 (+)	1182	WP_032876157.1	LCP family protein	-
M8970_RS12370	-	2532023..2533099 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M8970_RS12375	-	2533232..2534428 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=690728 M8970_RS12355 WP_007407484.1 2528705..2529868(-) (degS) [Bacillus velezensis strain UA0195]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=690728 M8970_RS12355 WP_007407484.1 2528705..2529868(-) (degS) [Bacillus velezensis strain UA0195]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951