Detailed information NTG0689394

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OSU72_RS12185
• Genome accession: NZ_CP113103
• Coordinates: 2830977..2832098 (+)
• Length: 373 a.a.
• NCBI ID: WP_003948877.1
• Uniprot ID: A0ABR4S230
• Organism: Streptomyces sp. NA13
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2825977..2837098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OSU72_RS12165 (OSU72_12165)	-	2826406..2826627 (-)	222	WP_003948872.1	hypothetical protein	-
OSU72_RS12170 (OSU72_12170)	-	2826739..2828481 (-)	1743	WP_267812086.1	BACON domain-containing protein	-
OSU72_RS12175 (OSU72_12175)	-	2828760..2829335 (+)	576	WP_003948874.1	dihydrofolate reductase family protein	-
OSU72_RS12180 (OSU72_12180)	radA/sms	2829389..2830807 (+)	1419	WP_003948876.1	DNA repair protein RadA	Machinery gene
OSU72_RS12185 (OSU72_12185)	disA	2830977..2832098 (+)	1122	WP_003948877.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OSU72_RS12190 (OSU72_12190)	-	2832178..2832996 (-)	819	WP_235617846.1	hypothetical protein	-
OSU72_RS12195 (OSU72_12195)	-	2833352..2834101 (+)	750	WP_008404973.1	phosphatase PAP2 family protein	-
OSU72_RS12200 (OSU72_12200)	-	2834214..2835266 (+)	1053	WP_008404974.1	A/G-specific adenine glycosylase	-
OSU72_RS12205 (OSU72_12205)	-	2835485..2836024 (+)	540	WP_003948881.1	SigE family RNA polymerase sigma factor	-
OSU72_RS12210 (OSU72_12210)	-	2836045..2836713 (+)	669	WP_030309702.1	lipoprotein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40243.11 Da
• Isoelectric Point: 5.1034

>NTDB_id=689394 OSU72_RS12185 WP_003948877.1 2830977..2832098(+) (disA) [Streptomyces sp. NA13]
MAANDRATAPGKSGGPGADGLMRASLSAVAPGTQLRDGLERILRGNTGGLIVLGWDRTVESMCTGGFVLDVEFSATRLRE
LCKLDGGIVLDKDLTKILRAGVQLVPDPTIPTDETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIAAEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVDEALAELGKLSHTELLELPVVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAI
IDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=689394 OSU72_RS12185 WP_003948877.1 2830977..2832098(+) (disA) [Streptomyces sp. NA13]
GTGGCAGCCAATGACCGGGCAACGGCCCCCGGCAAGTCCGGCGGGCCCGGTGCCGACGGGCTGATGCGTGCCTCGCTGAG
CGCCGTCGCCCCCGGCACCCAGCTGCGGGACGGGCTGGAGCGGATTCTGCGGGGGAACACCGGCGGACTCATCGTGCTCG
GCTGGGACAGGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTCGAGTTCTCGGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACCTCACCAAGATCCTGCGCGCCGGAGTCCAGCTCGTCCCCGA
CCCGACCATCCCCACCGACGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGGTCAACTTCCCCGTGG
TCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCCGCCATC
CTCTCCCGCGCCAACCAGGCCCTCGCGACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCCGGCACGCTCTCGGC
GCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCACGGCCGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCGCCG
CCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGTCTGCTCGCCCTCCAGCTGGACGAGCTGATCGCCGGC
GTCGAGCCCGAACGCGAGCTGGTCGTCCGGGACTACGTGCCGGAACCCACGGCGAAGCGTTCCCGGACGGTGGACGAGGC
GCTGGCGGAGCTGGGCAAGCTCAGCCACACCGAGCTGCTCGAACTGCCCGTGGTGGCGCGGGCGCTCGGCTACACCGGCT
CGCCGGAGGCGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGCGGCTGCCCGGGGCCATC
ATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTGGCGGCCAGTGTGGACGACCTCCAGACGGTGGACGG
CGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• Helix-hairpin-helix motif (HHH_2) (323-358)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.761	0.432