Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   OHM49_RS09340 Genome accession   NZ_CP109940
Coordinates   1883406..1884155 (-) Length   249 a.a.
NCBI ID   WP_024394858.1    Uniprot ID   -
Organism   Streptococcus suis strain ID34572     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1878406..1889155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHM49_RS09335 (OHM49_09335) - 1882193..1882828 (-) 636 WP_024394859.1 hypothetical protein -
  OHM49_RS09340 (OHM49_09340) comE/comE2 1883406..1884155 (-) 750 WP_024394858.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  OHM49_RS09345 (OHM49_09345) - 1884170..1885039 (-) 870 WP_226313481.1 GHKL domain-containing protein -
  OHM49_RS09350 (OHM49_09350) - 1885499..1885654 (-) 156 WP_000794567.1 hypothetical protein -
  OHM49_RS09355 (OHM49_09355) comA 1885676..1886164 (-) 489 WP_249547176.1 ATP-binding cassette domain-containing protein Regulator
  OHM49_RS09360 (OHM49_09360) - 1886259..1887263 (+) 1005 WP_002935211.1 IS5 family transposase -
  OHM49_RS09365 (OHM49_09365) comA 1887367..1889022 (-) 1656 WP_249547177.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29364.89 Da        Isoelectric Point: 7.7531

>NTDB_id=682491 OHM49_RS09340 WP_024394858.1 1883406..1884155(-) (comE/comE2) [Streptococcus suis strain ID34572]
MNIIVLDDNIHHQLRLESALYDVARSLHIHINIECARTIQALREYMNQEDVNQIYFLDLEIGNQKNLGFEIAKEIRNNNP
YAVIIFVTSYSDLMPLVFQYHLSALDFIIKDLKETEFRNRLKQCLEQVIISFKKKSDGELLRYSYQNRTGICIPFSDILF
IQTSVKPHRLIIYTVDFIKEFYGTLNDILDLDSKNYFEKVDRSTIINVYNVTEYSSKTREVKFFEGTTCLVSRLRIKDVK
TRLRNKGII

Nucleotide


Download         Length: 750 bp        

>NTDB_id=682491 OHM49_RS09340 WP_024394858.1 1883406..1884155(-) (comE/comE2) [Streptococcus suis strain ID34572]
ATGAATATTATTGTTCTGGATGACAATATTCATCATCAGTTGCGACTAGAATCTGCTCTTTATGATGTAGCTCGGTCTTT
ACATATTCATATCAATATTGAATGTGCTAGAACAATACAGGCATTAAGAGAGTATATGAATCAAGAAGATGTAAATCAGA
TATATTTTCTAGATTTAGAAATTGGCAATCAAAAAAATTTAGGTTTTGAGATTGCTAAAGAAATAAGAAATAATAATCCT
TATGCAGTTATTATATTTGTGACTTCATATTCCGACCTGATGCCCCTAGTATTTCAATATCATCTTTCGGCATTAGATTT
TATTATTAAAGATCTTAAAGAAACAGAATTTCGTAATCGGTTAAAGCAGTGTTTGGAACAAGTAATAATTTCATTTAAGA
AAAAATCTGATGGGGAATTGTTAAGATATAGTTACCAGAACAGAACTGGTATCTGCATACCTTTTTCCGATATACTTTTT
ATTCAAACCTCAGTTAAACCGCATCGATTAATTATTTATACAGTAGATTTTATTAAAGAATTTTATGGTACTTTGAATGA
TATTCTAGATTTAGATAGTAAGAATTATTTTGAAAAAGTAGATCGTTCAACAATAATAAATGTGTATAATGTTACTGAGT
ACAGTTCGAAAACAAGAGAAGTAAAATTTTTTGAAGGAACAACATGTCTTGTATCTAGATTGAGAATTAAGGATGTAAAA
ACTAGATTAAGAAATAAAGGAATAATATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-121)

LytTr DNA-binding domain (LytTR)

(152-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.349

100

0.373
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.349

100

0.373
  comE Streptococcus mitis SK321

36.22

100

0.369
  comE Streptococcus pneumoniae Rx1

36.22

100

0.369
  comE Streptococcus pneumoniae D39

36.22

100

0.369
  comE Streptococcus pneumoniae R6

36.22

100

0.369
  comE Streptococcus pneumoniae TIGR4

36.22

100

0.369
  comE Streptococcus mitis NCTC 12261

36.22

100

0.369
  comE Streptococcus infantis strain Atu-4

36.145

100

0.361