Detailed information NTG0067337

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JSA_RS14110
• Genome accession: NZ_AP014921
• Coordinates: 2705262..2706149 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain JH4899
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2700262..2711149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JSA_RS14075	-	2700281..2700373 (+)	93	WP_010956583.1	hypothetical protein	-
JSA_RS14080 (JSA_2522)	-	2700481..2700978 (-)	498	WP_001065268.1	glutathione peroxidase	-
JSA_RS14085 (JSA_2523)	-	2700988..2701248 (-)	261	WP_001789910.1	hypothetical protein	-
JSA_RS14095	-	2701630..2701743 (-)	114	WP_011447078.1	hypothetical protein	-
JSA_RS14100 (JSA_2524)	-	2702402..2704402 (-)	2001	WP_000776751.1	ABC transporter permease	-
JSA_RS14105 (JSA_2525)	-	2704399..2705154 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JSA_RS14110 (JSA_2526)	braS	2705262..2706149 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JSA_RS14115 (JSA_2527)	braR	2706160..2706825 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JSA_RS14120 (JSA_2528)	-	2706851..2707051 (-)	201	WP_000604732.1	hypothetical protein	-
JSA_RS14125 (JSA_2529)	-	2707249..2708673 (+)	1425	WP_000953744.1	alkaline phosphatase	-
JSA_RS15120	-	2708733..2708834 (-)	102	WP_000731972.1	SE2200 family small protein	-
JSA_RS14135 (JSA_2530)	-	2708956..2709411 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JSA_RS14140 (JSA_2531)	-	2709656..2710417 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=67337 JSA_RS14110 WP_000143419.1 2705262..2706149(-) (braS) [Staphylococcus aureus strain JH4899]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=67337 JSA_RS14110 WP_000143419.1 2705262..2706149(-) (braS) [Staphylococcus aureus strain JH4899]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997