Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OG226_RS22920 Genome accession   NZ_CP108463
Coordinates   5222405..5223463 (+) Length   352 a.a.
NCBI ID   WP_328686396.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01261     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5217405..5228463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG226_RS22905 (OG226_22865) - 5218083..5218940 (+) 858 WP_329349874.1 hypothetical protein -
  OG226_RS22910 (OG226_22870) - 5218951..5220660 (-) 1710 WP_329349875.1 hypothetical protein -
  OG226_RS22915 (OG226_22875) radA/sms 5220859..5222268 (+) 1410 WP_328680450.1 DNA repair protein RadA Machinery gene
  OG226_RS22920 (OG226_22880) disA 5222405..5223463 (+) 1059 WP_328686396.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OG226_RS22925 (OG226_22885) - 5223489..5224301 (-) 813 WP_329349876.1 hypothetical protein -
  OG226_RS22930 (OG226_22890) - 5224505..5225449 (+) 945 WP_329349877.1 A/G-specific adenine glycosylase -
  OG226_RS22935 (OG226_22895) - 5225791..5226330 (+) 540 WP_019064956.1 SigE family RNA polymerase sigma factor -
  OG226_RS22940 (OG226_22900) - 5226441..5227034 (+) 594 WP_328686397.1 hypothetical protein -
  OG226_RS22945 (OG226_22905) cseB 5227159..5227866 (+) 708 WP_328680456.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 37978.60 Da        Isoelectric Point: 4.9779

>NTDB_id=661091 OG226_RS22920 WP_328686396.1 5222405..5223463(+) (disA) [Streptomyces sp. NBC_01261]
MRASLSAAAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFILDVEFTATRLRELCKLDGGIVVSSDLSKILRAG
VQLVPDPNIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSTVVQRLEMVRLIATEIAGYVVELGTDGRLLALQLEELIAGVEPERELVVRDYVPEPTAKRS
RTVNEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=661091 OG226_RS22920 WP_328686396.1 5222405..5223463(+) (disA) [Streptomyces sp. NBC_01261]
ATGCGCGCCTCACTGAGCGCCGCGGCCCCTGGCACGGCCCTGCGCGACGGCCTGGAGAGAATCCTCCGCGGCAACACGGG
CGGCCTCATCGTGCTCGGTTCCGACAAGACCGTAGAAGCGATGTGCACAGGCGGTTTCATCCTGGACGTGGAGTTCACGG
CCACGCGCCTACGAGAACTTTGCAAGCTGGACGGCGGCATCGTCGTCTCCTCGGACCTCTCCAAGATCCTCCGAGCGGGC
GTCCAACTGGTCCCCGACCCCAACATCCCCACCGAGGAGACGGGCACCCGTCACCGCACGGCGGACCGAGTGAGCAAACA
GGTCTCCTTCCCGGTGGTCTCCGTCTCCCAGTCCATGCGCCTGATCGCTCTCTACGTAGACGGCCAACGCCGCGTGCTGG
AGGACTCGGCGGCGATCCTGTCCCGCGCCAACCAGGCTCTCGCCACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTG
GCGGGCACGCTGTCGGCCCTGGAGATCGAGGACCTGGTGACGGTCCGAGACGTGTCAACGGTGGTCCAACGTCTGGAAAT
GGTCCGTCTGATCGCGACCGAGATCGCCGGATACGTCGTGGAGCTCGGCACGGACGGCCGCCTGCTCGCCCTCCAGCTGG
AGGAGTTGATCGCGGGCGTGGAACCGGAACGTGAGCTAGTAGTACGCGACTACGTCCCCGAGCCCACGGCCAAACGCTCC
CGCACGGTGAACGAAGCCCTGGCCGAACTGGACGCGCTCTCCCACGCGGAGCTCCTCGAACTCCCCACCGTGGCCCGCGC
GTTGGGCTACACCGGCTCCCCCGAGGCCCTCGACTCGGCGGTGTCCCCCCGAGGCTTCCGTCTCCTGGCGAAGGTCCCGC
GCCTCCCCGGCGCGATCATCGACCGCCTGGTGGAGCACTTCGGAGGCCTGCAGAAACTCCTGGCGGCAAGCGTCGACGAC
CTGCAGACGGTGGACGGCGTGGGCGAGGCAAGGGCACGCAGCGTCCGAGAGGGCCTCTCCCGCCTGGCGGAATCGTCGAT
CCTGGAACGCTACGTATAA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

Helix-hairpin-helix motif (HHH_2)

(302-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.376

98.295

0.446