Detailed information NTG0654978

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG420_RS20945
• Genome accession: NZ_CP108147
• Coordinates: 4602114..4603172 (+)
• Length: 352 a.a.
• NCBI ID: WP_328834341.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00169
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4597114..4608172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG420_RS20930 (OG420_20905)	-	4597810..4598667 (+)	858	WP_328933568.1	hypothetical protein	-
OG420_RS20935 (OG420_20910)	-	4598671..4600365 (-)	1695	WP_405880116.1	BACON domain-containing protein	-
OG420_RS20940 (OG420_20915)	radA/sms	4600567..4601976 (+)	1410	WP_266769766.1	DNA repair protein RadA	Machinery gene
OG420_RS20945 (OG420_20920)	disA	4602114..4603172 (+)	1059	WP_328834341.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG420_RS20950 (OG420_20925)	-	4603217..4604047 (-)	831	WP_328933566.1	hypothetical protein	-
OG420_RS20955 (OG420_20930)	-	4604430..4605371 (+)	942	WP_328933565.1	A/G-specific adenine glycosylase	-
OG420_RS20960 (OG420_20935)	-	4605672..4606211 (+)	540	WP_019064956.1	SigE family RNA polymerase sigma factor	-
OG420_RS20965 (OG420_20940)	-	4606199..4606888 (+)	690	WP_405880119.1	hypothetical protein	-
OG420_RS20970 (OG420_20945)	cseB	4607034..4607741 (+)	708	WP_328830754.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 352 a.a.
• Molecular weight: 38034.67 Da
• Isoelectric Point: 4.7751

>NTDB_id=654978 OG420_RS20945 WP_328834341.1 4602114..4603172(+) (disA) [Streptomyces sp. NBC_00169]
MRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFILDVEFTATRLRELCKLDGGIVVSSDLSKILRAG
VQLVPDPDIPTEETGTRHRTADRVSKQVAFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVVQRLEMVRLIATEIAEYVVELGTDGRLLALQLEELIAGVEPERELVVRDYVPEPTAKRS
RTVDEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1059 bp

>NTDB_id=654978 OG420_RS20945 WP_328834341.1 4602114..4603172(+) (disA) [Streptomyces sp. NBC_00169]
ATGCGCGCCTCACTGAGCGCCGTGGCCCCCGGCACGGCGTTGCGCGACGGCCTGGAGCGCATCCTCCGCGGCAACACGGG
CGGCCTCATCGTGCTCGGTTCCGACAAGACCGTCGAAGCGATGTGCACGGGCGGCTTCATCCTGGACGTCGAGTTCACGG
CCACGCGCCTGCGCGAACTGTGCAAGCTCGACGGCGGCATCGTGGTGTCGTCCGATCTCTCCAAGATCCTCCGGGCGGGT
GTCCAGCTGGTCCCCGACCCGGACATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGCGTCAGCAAACA
GGTCGCCTTCCCGGTGGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCCCTCTACGTGGACGGCCAGCGACGCGTCCTGG
AGGACTCGGCGGCGATCCTGTCCCGCGCCAACCAGGCCCTGGCGACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTG
GCGGGAACGTTGTCAGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCCGCGGTGGTCCAGCGGCTGGAGAT
GGTCCGGCTGATCGCCACCGAAATCGCCGAGTACGTAGTGGAGTTGGGCACGGACGGCCGCCTGCTCGCCCTCCAGCTGG
AGGAGTTGATCGCGGGCGTGGAGCCGGAGCGCGAACTCGTCGTACGCGACTACGTCCCCGAGCCCACGGCCAAACGATCC
CGCACGGTGGACGAGGCACTCGCCGAACTCGACGCCCTCTCCCACGCGGAGCTCCTCGAACTCCCCACCGTGGCCCGCGC
GTTGGGCTACACCGGCTCCCCCGAGGCCCTCGACTCGGCGGTCTCCCCCCGCGGCTTCCGCCTGCTGGCCAAGGTCCCGC
GCCTCCCCGGCGCGATCATCGACCGCCTGGTCGAGCACTTCGGCGGCCTGCAGAAACTCCTGGCGGCAAGCGTCGACGAC
CTGCAGACGGTCGACGGCGTGGGCGAAGCGCGGGCCCGCAGCGTCCGAGAGGGCCTCTCCCGCCTGGCGGAGTCCTCGAT
CCTCGAACGCTACGTCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (133-275)

• Helix-hairpin-helix motif (HHH_2) (302-337)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (16-129)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.665	98.295	0.449