Detailed information NTG0653600

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG446_RS16450
• Genome accession: NZ_CP108100
• Coordinates: 3673273..3674397 (+)
• Length: 374 a.a.
• NCBI ID: WP_114245192.1
• Uniprot ID: A0ABY9IUC4
• Organism: Streptomyces sp. NBC_00236
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3668273..3679397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG446_RS16435 (OG446_16450)	-	3668735..3669583 (+)	849	WP_328894755.1	hypothetical protein	-
OG446_RS16440 (OG446_16455)	-	3669611..3671551 (-)	1941	WP_328894756.1	hypothetical protein	-
OG446_RS16445 (OG446_16460)	radA/sms	3671736..3673148 (+)	1413	WP_148020034.1	DNA repair protein RadA	Machinery gene
OG446_RS16450 (OG446_16465)	disA	3673273..3674397 (+)	1125	WP_114245192.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG446_RS16455 (OG446_16470)	-	3674680..3675504 (-)	825	WP_328894757.1	hypothetical protein	-
OG446_RS16460 (OG446_16475)	-	3675842..3676744 (+)	903	WP_328894758.1	A/G-specific adenine glycosylase	-
OG446_RS16465 (OG446_16480)	-	3676951..3677595 (+)	645	WP_328894759.1	SigE family RNA polymerase sigma factor	-
OG446_RS16470 (OG446_16485)	-	3677583..3678347 (+)	765	WP_328894760.1	hypothetical protein	-
OG446_RS16475 (OG446_16490)	cseB	3678358..3679062 (+)	705	WP_328894761.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40372.27 Da
• Isoelectric Point: 4.9352

>NTDB_id=653600 OG446_RS16450 WP_114245192.1 3673273..3674397(+) (disA) [Streptomyces sp. NBC_00236]
MAASDRAASPGKSGQGTGNEALMRASLTAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELAKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCNFPVVSVSQSMHLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=653600 OG446_RS16450 WP_114245192.1 3673273..3674397(+) (disA) [Streptomyces sp. NBC_00236]
GTGGCAGCCAGCGACCGGGCAGCATCGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGTT
GACCGCCGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATCCTCCGTGGCAACACCGGCGGGCTGATCGTGC
TCGGCATGGACAGGACCGTCGAGTCGATGTGCACCGGCGGCTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTCGCCAAGCTCGACGGGGCACTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGCGTCCAGCTGGTCCC
GGACGCCTCGATCCCCACCGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGGGTCTCCAAGCAGTGCAACTTCCCGG
TCGTCTCGGTCTCGCAGTCGATGCACCTCATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCCGCCGCG
ATCCTCTCCCGCGCCAACCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTCCGGCTCGACGAGGTCGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGACGGCGGTCGCCCAGCGGCTGGAGATGGTCCGCCGGATCG
CGACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACCGACGGCCGGCTCCTCTCGCTCCAGCTCGACGAGTTGATCGCG
GGCGTGGAGCCGGAGCGCGAGCTGGTCGTGCGCGACTACGTGCCGGAGCCGACCGCGAAGCGCTCCCGCACGGTGGCGGA
GGCGCTCACCGAGCTGGACGCGCTGTCCCACACCGAGCTGCTCGAACTCCCGGTCGTGGCAAGGGCGCTTGGCTACAGCG
GCTCCCCGGAGACGCTCGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGCGCCTGCCCGGGGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCACGGGCGCGCAGCGTGCGCGAGGGCCTGTCGCGGCTGGCCGAGTCGTCGATCCTCGAACGGTACG
TGTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436