Detailed information NTG0650758

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHT74_RS17010
• Genome accession: NZ_CP107983
• Coordinates: 3797167..3798291 (+)
• Length: 374 a.a.
• NCBI ID: WP_266665127.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00354
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3792167..3803291

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHT74_RS16995 (OHT74_17020)	-	3793159..3794025 (+)	867	WP_266996351.1	hypothetical protein	-
OHT74_RS17000 (OHT74_17025)	-	3794189..3795289 (-)	1101	Protein_3372	sigma-70 family RNA polymerase sigma factor	-
OHT74_RS17005 (OHT74_17030)	radA/sms	3795509..3796912 (+)	1404	WP_328620641.1	DNA repair protein RadA	Machinery gene
OHT74_RS17010 (OHT74_17035)	disA	3797167..3798291 (+)	1125	WP_266665127.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHT74_RS17015 (OHT74_17040)	-	3798400..3799137 (-)	738	WP_328620642.1	hypothetical protein	-
OHT74_RS17020 (OHT74_17045)	-	3799361..3799783 (+)	423	WP_328620643.1	phosphatase PAP2 family protein	-
OHT74_RS17025 (OHT74_17050)	-	3799805..3800758 (+)	954	WP_266665131.1	A/G-specific adenine glycosylase	-
OHT74_RS17030 (OHT74_17055)	-	3800942..3801514 (+)	573	WP_030158464.1	SigE family RNA polymerase sigma factor	-
OHT74_RS17035 (OHT74_17060)	-	3801553..3802191 (+)	639	WP_266672827.1	hypothetical protein	-
OHT74_RS17040 (OHT74_17065)	cseB	3802262..3802975 (+)	714	WP_266665133.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40334.30 Da
• Isoelectric Point: 5.0226

>NTDB_id=650758 OHT74_RS17010 WP_266665127.1 3797167..3798291(+) (disA) [Streptomyces sp. NBC_00354]
MAAKDGAAASGKSGASSKQEAMMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKSVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVDEALPALDALTHPELLELGIVARALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=650758 OHT74_RS17010 WP_266665127.1 3797167..3798291(+) (disA) [Streptomyces sp. NBC_00354]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCGGGCGCGAGCTCCAAGCAGGAGGCCATGATGCGCGCCTCGCT
GAGCGCGGTCGCACCTGGTCAGCCCCTGCGTGACGGTCTGGAACGGATCGTCCGCGGCAACACCGGCGGCCTCATCGTCC
TCGGGATGGACAAGTCCGTCGAGGCGATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTGATCCTGGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTCCAGCTGGTGCC
TGACGCGTCGATCCCGACGGAGGAGACGGGCACCCGTCACCGCACCGCGGACCGCGTCTCGAAGCAGTGCGGCTTCCCCG
TGGTGTCGGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGGGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCGGGGACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTCACGGTGCGCGACGTGACGGCGGTCGCGCAGCGGCTGGAAATGGTTCGCCGCATTG
CCACGGAAATCGCTGAATACGTGGTCGAGCTGGGTACGGACGGGCGACTGCTGTCGCTCCAGCTGGACGAGCTGACGGTC
GGCATCGAGCAGGAGCGGGAGCTGGTGATCCGGGACTACGTGCCGGAGCCGACGGCGAAGCGCTCCCGCACGGTGGACGA
GGCGCTGCCGGCGCTGGACGCCCTGACGCATCCGGAGCTGCTGGAGCTCGGCATCGTGGCGCGCGCGCTGGGGTACACGG
GCTCGCCGGAGACGCTCGACTCGGCGGTGTCCCCGCGGGGGTACCGGCTGCTGGCGAAGGTTCCGCGGCTGCCGGGGGCC
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGCCTGCAGAAGTTGCTGGCCGCGTCGGTGGACGATCTGCAGACGGTCGA
CGGGGTCGGGGAAGCCCGTGCGCGGAGCGTCCGCGAGGGCCTGTCCCGCCTGGCGGAGTCCTCGATCCTCGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441