Detailed information NTG0648706

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHU74_RS20510
• Genome accession: NZ_CP107907
• Coordinates: 4418281..4419405 (-)
• Length: 374 a.a.
• NCBI ID: WP_330297894.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00454
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4413281..4424405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHU74_RS20480 (OHU74_20485)	cseB	4413406..4414119 (-)	714	WP_371617263.1	two-component system response regulator CseB	-
OHU74_RS20485 (OHU74_20490)	-	4414174..4414833 (-)	660	WP_371619744.1	hypothetical protein	-
OHU74_RS20490 (OHU74_20495)	-	4414860..4415420 (-)	561	WP_069920779.1	SigE family RNA polymerase sigma factor	-
OHU74_RS20495 (OHU74_20500)	-	4415596..4416582 (-)	987	WP_371617264.1	A/G-specific adenine glycosylase	-
OHU74_RS20500 (OHU74_20505)	-	4416600..4417208 (-)	609	WP_371617265.1	phosphatase PAP2 family protein	-
OHU74_RS20505 (OHU74_20510)	-	4417379..4418188 (+)	810	WP_371617266.1	hypothetical protein	-
OHU74_RS20510 (OHU74_20515)	disA	4418281..4419405 (-)	1125	WP_330297894.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHU74_RS20515 (OHU74_20520)	radA/sms	4419674..4421089 (-)	1416	WP_330297895.1	DNA repair protein RadA	Machinery gene
OHU74_RS20520 (OHU74_20525)	-	4421285..4423123 (+)	1839	WP_371617267.1	hypothetical protein	-
OHU74_RS20525 (OHU74_20530)	-	4423136..4424014 (-)	879	WP_371617268.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40330.32 Da
• Isoelectric Point: 5.1222

>NTDB_id=648706 OHU74_RS20510 WP_330297894.1 4418281..4419405(-) (disA) [Streptomyces sp. NBC_00454]
MAAKDGAAASGKSGASSKQEAMMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKSVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDLTKILRAGVQLVPDASIHTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVGAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELAIVAKALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=648706 OHU74_RS20510 WP_330297894.1 4418281..4419405(-) (disA) [Streptomyces sp. NBC_00454]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCGGGCGCGAGCTCCAAGCAGGAGGCCATGATGCGTGCCTCGCT
GAGCGCGGTCGCACCCGGTCAGCCGCTGCGCGACGGACTCGAACGGATCGTCCGCGGCAACACCGGCGGGCTCATCGTCC
TCGGCATGGACAAGTCCGTGGAAGCGATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTGATCCTGGACAAGGACCTCACCAAGATCCTGCGGGCGGGCGTGCAGCTCGTTCC
GGACGCCTCCATCCACACGGAGGAGACCGGTACCCGGCACCGCACCGCGGACCGCGTCTCGAAGCAGTGCGGGTTCCCGG
TGGTCTCGGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGCGAGCGGCGCGTGCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGGGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCGGCGCGGTGGCGCAGCGGCTGGAAATGGTCCGCCGGATCG
CGACGGAAATCGCTGAATACGTGGTGGAGCTCGGCACGGACGGCCGACTGCTGTCGCTCCAGCTGGACGAGCTGACGGTC
GGGATCGAGCAGGAGCGCGAGCTGGTCATCCGGGACTACGTGCCGGAGCCGACGGCGAAGCGGTCGCGGACGGTGGAGGA
AGCGCTGCCCGCGCTGGACGCGCTGACCCACCCGGAGCTGCTGGAACTGGCGATCGTGGCGAAGGCGCTGGGGTACACCG
GTTCGCCGGAGACGCTGGACTCGGCGGTGTCCCCGCGGGGCTACCGGCTGCTGGCGAAGGTTCCCCGGCTGCCGGGCGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGTGGCCTGCAGAAGCTGCTGGCCGCCTCCGTGGACGACCTGCAGACGGTCGA
CGGGGTCGGCGAGGCGCGTGCGCGCAGCGTCCGCGAGGGGCTGTCCCGGTTGGCGGAGTCCTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.983	96.524	0.444