Detailed information NTG0646123

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHO83_RS21380
• Genome accession: NZ_CP107783
• Coordinates: 4763351..4764475 (+)
• Length: 374 a.a.
• NCBI ID: WP_266673013.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00569
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4758351..4769475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHO83_RS21365 (OHO83_21380)	-	4758897..4759826 (+)	930	WP_266673019.1	hypothetical protein	-
OHO83_RS21370 (OHO83_21385)	-	4759859..4761574 (-)	1716	WP_266673017.1	hypothetical protein	-
OHO83_RS21375 (OHO83_21390)	radA/sms	4761829..4763238 (+)	1410	WP_266673015.1	DNA repair protein RadA	Machinery gene
OHO83_RS21380 (OHO83_21395)	disA	4763351..4764475 (+)	1125	WP_266673013.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHO83_RS21385 (OHO83_21400)	-	4765165..4765959 (-)	795	WP_266673012.1	hypothetical protein	-
OHO83_RS21390 (OHO83_21405)	-	4766145..4766786 (+)	642	WP_266673011.1	phosphatase PAP2 family protein	-
OHO83_RS21395 (OHO83_21410)	-	4766787..4767434 (-)	648	WP_330279732.1	response regulator transcription factor	-
OHO83_RS21400 (OHO83_21415)	-	4767431..4769032 (-)	1602	WP_330279733.1	histidine kinase	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40341.21 Da
• Isoelectric Point: 4.9304

>NTDB_id=646123 OHO83_RS21380 WP_266673013.1 4763351..4764475(+) (disA) [Streptomyces sp. NBC_00569]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=646123 OHO83_RS21380 WP_266673013.1 4763351..4764475(+) (disA) [Streptomyces sp. NBC_00569]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGTGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCGGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTGCGGGCGGGCGTCCAGTTGGTGCC
CGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCAGCTTCCCCG
TGGTCTCGGTGTCGCAGTCGATGCGGCTCATCGCCCTCTACGTGGACGGGCAGCGGCGCGTCCTCGAGGACTCGGCCGCG
ATTCTCTCGCGGGCGAATCAGGCGCTGGCCACTCTTGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACACTCTC
CGCGCTCGAGATCGAGGATCTCGTGACCGTGCGGGATGTGACCGCGGTCGCGCAGCGGCTGGAAATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGATGGGCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGGGTGGAGCCGGAGCGGGAGCTCGTCGTTCGGGACTACGTGCCCGAACCCACGGCCAAGCGGTCCCGGACCGTCGACGA
GGCCCTGTTCGAACTCGACGCGCTGACGCATGCCGAGCTTCTCGAACTGCCCACTGTGGCACGCGCGTTGGGGTACACCG
GGTCTCCGGAGACCCTGGACTCGGCCGTTTCGCCTCGTGGGTTCCGGCTGTTGGCGAAGGTGCCTCGGCTGCCCGGGGCC
ATCATTGAGCGGCTTGTCGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCCAGCGTCGACGATCTGCAGACCGTGGA
CGGCGTCGGCGAGGCCCGCGCCCGGAGCGTGCGGGAAGGGCTCTCGCGGTTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433