Detailed information NTG0646050

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG734_RS28080
• Genome accession: NZ_CP107780
• Coordinates: 6484857..6485981 (-)
• Length: 374 a.a.
• NCBI ID: WP_330290260.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00576
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 6479857..6490981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG734_RS28055 (OG734_28115)	-	6480678..6481628 (-)	951	WP_330290255.1	A/G-specific adenine glycosylase	-
OG734_RS28060 (OG734_28120)	-	6481875..6482690 (+)	816	WP_330290256.1	oxidoreductase	-
OG734_RS28065 (OG734_28125)	-	6482740..6483087 (+)	348	WP_330290257.1	hypothetical protein	-
OG734_RS28070 (OG734_28130)	-	6483140..6483730 (+)	591	WP_330290258.1	TetR/AcrR family transcriptional regulator	-
OG734_RS28075 (OG734_28135)	-	6483904..6484758 (+)	855	WP_330290259.1	hypothetical protein	-
OG734_RS28080 (OG734_28140)	disA	6484857..6485981 (-)	1125	WP_330290260.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG734_RS28085 (OG734_28145)	radA/sms	6486063..6487472 (-)	1410	WP_330290261.1	DNA repair protein RadA	Machinery gene
OG734_RS28090 (OG734_28150)	-	6487691..6489493 (+)	1803	WP_330290262.1	hypothetical protein	-
OG734_RS28095 (OG734_28155)	-	6489504..6490379 (-)	876	WP_330290263.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 39889.69 Da
• Isoelectric Point: 4.9130

>NTDB_id=646050 OG734_RS28080 WP_330290260.1 6484857..6485981(-) (disA) [Streptomyces sp. NBC_00576]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFSATRLR
ELCKLDGGIVVSSDLSKILRAGVQLVPDPMIPTEETGTRHRTADRVSKQVGFSVISVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVVQRLEMVRLIATEIAGYVLELGTDGRLLALQLEELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDALSHAELLELSTVAKALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=646050 OG734_RS28080 WP_330290260.1 6484857..6485981(-) (disA) [Streptomyces sp. NBC_00576]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCTGTGGCACCCGGCACGGCGCTGCGCGACGGGCTTGAACGGATTCTCCGCGGTAACACCGGCGGACTCATCGTGC
TCGGCTCCGACAAGACTGTCGAAGCGATGTGCACAGGCGGTTTCGTCCTGGACGTCGAGTTCTCGGCGACGCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGGTCTCCTCGGACCTGTCCAAGATCCTGCGGGCCGGCGTACAGCTGGTCCC
CGACCCGATGATCCCCACCGAGGAGACAGGCACCCGGCACCGCACCGCCGACCGCGTGTCGAAACAGGTGGGCTTCTCGG
TCATCTCGGTCTCCCAGTCGATGAGACTCATCGCGCTGTACGTGGACGGCCAGCGCCGGGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCGAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCGGCGGTGGTGCAGCGTCTGGAGATGGTCCGCCTCATCG
CGACGGAAATCGCCGGGTACGTGCTCGAGCTGGGCACCGACGGGCGGCTTCTGGCCCTCCAGCTGGAGGAGTTGATCGCG
GGCGTGGAGCCGGAGCGCGAACTGGTGGTCCGGGACTACGTACCCGAGCCGACCGCCAAACGCTCGCGCACGGTCGACGA
GGCGCTCGCGGAACTCGACGCGCTCAGCCACGCCGAGCTGCTCGAACTCTCCACGGTGGCCAAGGCCCTGGGCTACACGG
GCTCACCCGAGACCCTCGACTCGGCGGTCTCCCCCCGCGGCTTCCGCCTCCTGGCGAAGGTGCCACGCCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAACACTTCGGCGGCCTGCAGAAGCTGCTGGCGGCGAGCGTCGACGACCTCCAGACGGTGGA
CGGGGTCGGCGAGGCGAGGGCGCGCAGCGTGCGGGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATTCTGGAGCGGTACG
TGTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.983	96.524	0.444