Detailed information NTG0645631

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: L1A12_RS09550
• Genome accession: NZ_CP090882
• Coordinates: 1859451..1859912 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain CH2241
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1854451..1864912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A12_RS09520 (L1A12_09520)	-	1854755..1855579 (-)	825	WP_001809383.1	membrane protein insertase YidC	-
L1A12_RS09525 (L1A12_09525)	rnpA	1855554..1855925 (-)	372	WP_000739244.1	ribonuclease P protein component	-
L1A12_RS10690	-	1855942..1856073 (-)	132	WP_000768904.1	hypothetical protein	-
L1A12_RS09530 (L1A12_09530)	-	1856074..1857264 (-)	1191	WP_000167765.1	acetate kinase	-
L1A12_RS09535 (L1A12_09535)	comYH	1857315..1858268 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
L1A12_RS09540 (L1A12_09540)	-	1858329..1858923 (-)	595	Protein_1869	methyltransferase domain-containing protein	-
L1A12_RS09545 (L1A12_09545)	comGG/cglG	1859060..1859473 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
L1A12_RS09550 (L1A12_09550)	comGF/cglF	1859451..1859912 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
L1A12_RS09555 (L1A12_09555)	comGE/cglE	1859875..1860177 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
L1A12_RS09560 (L1A12_09560)	comGD/cglD	1860140..1860544 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
L1A12_RS09565 (L1A12_09565)	comGC/cglC	1860537..1860863 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
L1A12_RS09570 (L1A12_09570)	comGB/cglB	1860865..1861881 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
L1A12_RS09575 (L1A12_09575)	comGA/cglA/cilD	1861829..1862770 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
L1A12_RS09580 (L1A12_09580)	-	1862846..1863211 (-)	366	WP_000286415.1	DUF1033 family protein	-
L1A12_RS09585 (L1A12_09585)	-	1863362..1864420 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=645631 L1A12_RS09550 WP_000250542.1 1859451..1859912(-) (comGF/cglF) [Streptococcus pneumoniae strain CH2241]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=645631 L1A12_RS09550 WP_000250542.1 1859451..1859912(-) (comGF/cglF) [Streptococcus pneumoniae strain CH2241]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909