Detailed information NTG0645309

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: L0999_RS06080
• Genome accession: NZ_CP090870
• Coordinates: 1140782..1141669 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain SAUR_BFS62
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1135782..1146669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L0999_RS06050 (L0999_06050)	-	1135802..1135894 (+)	93	WP_010956583.1	hypothetical protein	-
L0999_RS06055 (L0999_06055)	-	1136002..1136499 (-)	498	WP_001065268.1	glutathione peroxidase	-
L0999_RS06060 (L0999_06060)	-	1136509..1136769 (-)	261	WP_001791974.1	hypothetical protein	-
L0999_RS06065 (L0999_06065)	-	1137151..1137264 (-)	114	Protein_1165	hypothetical protein	-
L0999_RS06070 (L0999_06070)	-	1137923..1139923 (-)	2001	WP_000776751.1	ABC transporter permease	-
L0999_RS06075 (L0999_06075)	-	1139920..1140675 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
L0999_RS06080 (L0999_06080)	braS	1140782..1141669 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
L0999_RS06085 (L0999_06085)	braR	1141680..1142345 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
L0999_RS06090 (L0999_06090)	-	1142371..1142571 (-)	201	WP_000604730.1	hypothetical protein	-
L0999_RS06095 (L0999_06095)	-	1142769..1144193 (+)	1425	WP_000953755.1	alkaline phosphatase	-
L0999_RS14000	-	1144253..1144354 (-)	102	WP_000731976.1	SE2200 family small protein	-
L0999_RS06105 (L0999_06105)	-	1144476..1144931 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
L0999_RS06110 (L0999_06110)	-	1145176..1145937 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=645309 L0999_RS06080 WP_000143425.1 1140782..1141669(-) (braS) [Staphylococcus aureus strain SAUR_BFS62]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=645309 L0999_RS06080 WP_000143425.1 1140782..1141669(-) (braS) [Staphylococcus aureus strain SAUR_BFS62]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1