Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NLY77_RS00355 Genome accession   NZ_CP100431
Coordinates   58656..59555 (+) Length   299 a.a.
NCBI ID   WP_024382136.1    Uniprot ID   -
Organism   Streptococcus suis strain 1521251     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53656..64555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS00330 (NLY77_00330) - 53661..54431 (+) 771 WP_002935304.1 membrane protein -
  NLY77_RS00335 (NLY77_00335) - 54434..56146 (+) 1713 WP_002935303.1 ABC transporter ATP-binding protein -
  NLY77_RS00340 (NLY77_00340) - 56248..56421 (+) 174 WP_002935301.1 hypothetical protein -
  NLY77_RS00345 (NLY77_00345) ruvB 56716..57717 (+) 1002 WP_002935300.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  NLY77_RS00350 (NLY77_00350) - 57785..58420 (+) 636 WP_024382137.1 HAD-IA family hydrolase -
  NLY77_RS00355 (NLY77_00355) comR 58656..59555 (+) 900 WP_024382136.1 helix-turn-helix domain-containing protein Regulator
  NLY77_RS00360 (NLY77_00360) - 59981..61030 (+) 1050 Protein_51 IS110 family transposase -
  NLY77_RS00365 (NLY77_00365) - 61691..62629 (-) 939 Protein_52 IS4 family transposase -
  NLY77_RS00370 (NLY77_00370) - 62769..63989 (+) 1221 WP_024394299.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35425.29 Da        Isoelectric Point: 4.6492

>NTDB_id=605058 NLY77_RS00355 WP_024382136.1 58656..59555(+) (comR) [Streptococcus suis strain 1521251]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPISKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=605058 NLY77_RS00355 WP_024382136.1 58656..59555(+) (comR) [Streptococcus suis strain 1521251]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAATTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATATCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.331

100

0.993
  comR Streptococcus suis 05ZYH33

99.331

100

0.993
  comR Streptococcus suis D9

61.462

100

0.619
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371