Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   K6J59_RS03650 Genome accession   NZ_AP018782
Coordinates   732289..733296 (+) Length   335 a.a.
NCBI ID   WP_005649027.1    Uniprot ID   Q4QNM6
Organism   Haemophilus influenzae strain CHBN-V-2 isolate 13H37     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 727289..738296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J59_RS03625 (CHBNV2_06850) aspS 727972..729738 (+) 1767 WP_005649039.1 aspartate--tRNA ligase -
  K6J59_RS03630 (CHBNV2_06860) nudB 729760..730233 (+) 474 WP_005666660.1 dihydroneopterin triphosphate diphosphatase -
  K6J59_RS03635 (CHBNV2_06870) - 730245..730985 (+) 741 WP_005649034.1 YebC/PmpR family DNA-binding transcriptional regulator -
  K6J59_RS03640 (CHBNV2_06880) ruvC 731032..731604 (+) 573 WP_005666663.1 crossover junction endodeoxyribonuclease RuvC -
  K6J59_RS03645 (CHBNV2_06890) ruvA 731667..732281 (+) 615 WP_005659994.1 Holliday junction branch migration protein RuvA Machinery gene
  K6J59_RS03650 (CHBNV2_06900) ruvB 732289..733296 (+) 1008 WP_005649027.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  K6J59_RS03655 (CHBNV2_06910) - 733348..733635 (-) 288 WP_005659998.1 DUF5339 domain-containing protein -
  K6J59_RS03660 (CHBNV2_06920) xerD 733808..734701 (-) 894 WP_005666666.1 site-specific tyrosine recombinase XerD -
  K6J59_RS03665 (CHBNV2_06930) - 734732..735898 (-) 1167 WP_005666667.1 3-phenylpropionate MFS transporter -
  K6J59_RS03670 (CHBNV2_06940) proC 735898..736713 (-) 816 WP_005649013.1 pyrroline-5-carboxylate reductase -
  K6J59_RS03675 (CHBNV2_06950) - 737379..738269 (+) 891 WP_005649010.1 replication initiation protein -

Sequence

Protein


Download         Length: 335 a.a.        Molecular weight: 37076.41 Da        Isoelectric Point: 4.7793

>NTDB_id=60238 K6J59_RS03650 WP_005649027.1 732289..733296(+) (ruvB) [Haemophilus influenzae strain CHBN-V-2 isolate 13H37]
MIEADRIISGQAKVDEDVIDRAIRPKLLADYVGQPQVREQMDIFIKAAKLRQDALDHLLIFGPPGLGKTTLANIVANEMG
VNIRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYSVEDLTSIVARSADCLNLELEQQAAFEVARRSRGTPRIANRLLRRVRDYADVRNGG
IISINVAKQALSMLDVDDAGFDYLDRKLLSAVIERFDGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIA
TSQTYRHFGLQKLSD

Nucleotide


Download         Length: 1008 bp        

>NTDB_id=60238 K6J59_RS03650 WP_005649027.1 732289..733296(+) (ruvB) [Haemophilus influenzae strain CHBN-V-2 isolate 13H37]
ATGATTGAAGCAGATAGAATTATTAGCGGGCAAGCTAAGGTTGATGAAGATGTTATCGACCGTGCTATTCGTCCTAAACT
ATTAGCAGATTATGTTGGGCAGCCGCAAGTACGCGAGCAGATGGATATTTTCATCAAGGCAGCCAAACTACGTCAAGATG
CCTTAGATCATTTATTGATTTTTGGCCCTCCAGGTTTGGGAAAAACAACGCTTGCTAATATTGTGGCAAATGAAATGGGC
GTGAATATTCGTACGACATCAGGGCCTGTATTAGAAAAAGCGGGAGATTTAGCCGCAATGCTAACCAATCTTGAACCGCA
TGATGTATTATTTATTGATGAAATCCATCGACTTTCCCCTGCGATTGAAGAAGTCCTTTATCCAGCAATGGAAGACTATC
AGTTGGATATTATGATTGGCGAAGGACCCGCTGCTCGTTCCATTAAATTAGATTTGCCCCCTTTTACTTTGGTTGGCGCG
ACCACTAGAGCGGGTTCTTTGACTTCTCCATTGCGTGATCGTTTTGGTATTGTGCAACGTTTGGAATTCTATTCTGTAGA
AGATTTAACATCTATCGTTGCAAGAAGTGCGGACTGTTTAAATCTTGAATTAGAACAACAAGCCGCTTTCGAGGTGGCTC
GTCGTTCACGAGGCACGCCTCGAATTGCAAACCGTTTATTACGACGTGTGCGTGATTATGCAGATGTACGTAATGGCGGT
ATTATTTCTATAAATGTGGCAAAACAAGCACTTTCAATGCTAGATGTAGACGATGCTGGATTTGATTATTTAGATAGAAA
GTTGTTGTCTGCAGTTATTGAGCGTTTTGACGGTGGGCCTGTGGGGCTAGATAATCTTGCCGCTGCGATCGGCGAAGAAC
GTGATACCATTGAAGATGTGTTAGAGCCTTATTTGATTCAACAGGGGTTTCTACAAAGAACGCCGCGTGGTCGTATTGCA
ACATCACAAACTTATCGCCATTTTGGTTTGCAGAAATTATCAGACTAG

Domains

Predicted by InterProScan.

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(23-181)

RuvB C-terminal winged helix domain (WHD_RuvB)

(259-328)

RuvB AAA lid domain (AAA_lid_4)

(184-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Bacillus subtilis subsp. subtilis str. 168

62.385

97.612

0.609
  ruvB Streptococcus pneumoniae TIGR4

57.975

97.313

0.564
  ruvB Streptococcus pneumoniae R6

57.975

97.313

0.564
  ruvB Streptococcus pneumoniae D39

57.975

97.313

0.564
  ruvB Helicobacter pylori 26695

54.633

93.433

0.51
  ruvB Synechocystis sp. PCC 6803

55.016

92.239

0.507

Multiple sequence alignment