Detailed information NTG0597760

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: K6K15_RS11305
• Genome accession: NZ_CP081851
• Coordinates: 2333582..2335774 (-)
• Length: 730 a.a.
• NCBI ID: WP_305014943.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain XJ-003
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2328582..2340774

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6K15_RS11275 (K6K15_11215)	-	2328747..2329031 (-)	285	WP_305014941.1	bacteriocin immunity protein	-
K6K15_RS11280 (K6K15_11220)	-	2329225..2329521 (-)	297	WP_003588783.1	bacteriocin immunity protein	-
K6K15_RS11285 (K6K15_11225)	-	2329623..2330978 (-)	1356	WP_019898905.1	threonine/serine exporter ThrE family protein	-
K6K15_RS11290 (K6K15_11230)	-	2331284..2331595 (-)	312	WP_003580849.1	hypothetical protein	-
K6K15_RS11295 (K6K15_11235)	-	2331668..2332018 (-)	351	WP_003567340.1	hypothetical protein	-
K6K15_RS11300 (K6K15_11240)	-	2332192..2333571 (-)	1380	WP_305014942.1	bacteriocin secretion accessory protein	-
K6K15_RS11305 (K6K15_11245)	comA	2333582..2335774 (-)	2193	WP_305014943.1	peptide cleavage/export ABC transporter	Regulator
K6K15_RS11310 (K6K15_11250)	-	2336101..2337021 (-)	921	WP_003574021.1	IS30 family transposase	-
K6K15_RS11315 (K6K15_11255)	-	2337132..2337320 (-)	189	Protein_2204	CPBP family intramembrane glutamate endopeptidase	-
K6K15_RS11320 (K6K15_11260)	-	2337454..2337717 (-)	264	WP_032795140.1	hypothetical protein	-
K6K15_RS11325 (K6K15_11265)	-	2337833..2338165 (-)	333	WP_003599808.1	hypothetical protein	-
K6K15_RS11330 (K6K15_11270)	-	2338421..2339068 (-)	648	WP_240031622.1	CPBP family intramembrane glutamic endopeptidase	-
K6K15_RS11335 (K6K15_11275)	-	2339070..2339261 (-)	192	WP_305014945.1	hypothetical protein	-
K6K15_RS11340 (K6K15_11280)	-	2339577..2339912 (-)	336	WP_003576308.1	bacteriocin immunity protein	-
K6K15_RS11345 (K6K15_11285)	-	2340031..2340627 (-)	597	WP_305014946.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81364.61 Da
• Isoelectric Point: 7.2445

>NTDB_id=597760 K6K15_RS11305 WP_305014943.1 2333582..2335774(-) (comA) [Lacticaseibacillus paracasei strain XJ-003]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDSSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIYALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEELNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=597760 K6K15_RS11305 WP_305014943.1 2333582..2335774(-) (comA) [Lacticaseibacillus paracasei strain XJ-003]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGAGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTACGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATTCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGGAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCTATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTTATGCGCTGGCAAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCTATTATCGAGGAATTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGCGGATCAGGAAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGCTGGTAAGTGAATGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.496	98.356	0.575
comA	Streptococcus pneumoniae Rx1	57.939	98.356	0.57
comA	Streptococcus pneumoniae D39	57.939	98.356	0.57
comA	Streptococcus pneumoniae R6	57.939	98.356	0.57
comA	Streptococcus mitis SK321	57.799	98.356	0.568
comA	Streptococcus pneumoniae TIGR4	57.521	98.356	0.566
comA	Streptococcus gordonii str. Challis substr. CH1	56.685	98.356	0.558
comA/nlmT	Streptococcus mutans UA159	54.571	98.904	0.54