Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M8286_RS02120 Genome accession   NZ_CP097577
Coordinates   423983..424624 (+) Length   213 a.a.
NCBI ID   WP_358638919.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 418983..429624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS02100 (M8286_02110) - 419284..420021 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M8286_RS02105 (M8286_02115) stkP 420021..422015 (+) 1995 WP_275601342.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M8286_RS02110 (M8286_02120) liaF 422303..422998 (+) 696 WP_012774984.1 cell wall-active antibiotics response protein LiaF -
  M8286_RS02115 (M8286_02125) - 422995..424011 (+) 1017 WP_002937028.1 sensor histidine kinase -
  M8286_RS02120 (M8286_02130) vraR 423983..424624 (+) 642 WP_358638919.1 response regulator transcription factor Regulator
  M8286_RS02125 (M8286_02135) - 424674..426074 (+) 1401 WP_029173958.1 Cof-type HAD-IIB family hydrolase -
  M8286_RS02130 (M8286_02140) - 426076..426447 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  M8286_RS02135 (M8286_02145) cysK 426473..427399 (-) 927 WP_002937015.1 cysteine synthase A -
  M8286_RS02140 (M8286_02150) - 427489..428121 (-) 633 WP_015646510.1 YigZ family protein -
  M8286_RS02145 (M8286_02155) comFA/cflA 428178..429470 (+) 1293 WP_275601344.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23836.45 Da        Isoelectric Point: 4.8969

>NTDB_id=595694 M8286_RS02120 WP_358638919.1 423983..424624(+) (vraR) [Streptococcus suis strain 3112]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEECLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=595694 M8286_RS02120 WP_358638919.1 423983..424624(+) (vraR) [Streptococcus suis strain 3112]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAATGTTTGGCTAAAGCATTAGAAGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTGGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTAACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAAACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413