Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   M2M89_RS09065 Genome accession   NZ_CP097130
Coordinates   1756460..1758343 (+) Length   627 a.a.
NCBI ID   WP_041850821.1    Uniprot ID   -
Organism   Bacillus subtilis strain S16     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1751460..1763343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2M89_RS09050 ymcA 1752497..1752928 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  M2M89_RS09055 cotE 1753190..1753735 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  M2M89_RS09060 hexA 1753868..1756444 (+) 2577 WP_064671396.1 DNA mismatch repair protein MutS Machinery gene
  M2M89_RS09065 hexB 1756460..1758343 (+) 1884 WP_041850821.1 DNA mismatch repair endonuclease MutL Machinery gene
  M2M89_RS09070 ymzD 1758742..1759197 (-) 456 WP_080332606.1 regulatory YrvL family protein -
  M2M89_RS09075 - 1759352..1759909 (-) 558 WP_038428985.1 hypothetical protein -
  M2M89_RS09080 pksA 1760030..1760647 (+) 618 WP_021479267.1 TetR/AcrR family transcriptional regulator -
  M2M89_RS09085 pksB 1760836..1761513 (+) 678 WP_029726478.1 MBL fold metallo-hydrolase -
  M2M89_RS09090 - 1761624..1761890 (+) 267 WP_120363368.1 hypothetical protein -
  M2M89_RS09095 fabD 1761887..1762753 (+) 867 WP_015715909.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70402.43 Da        Isoelectric Point: 6.0358

>NTDB_id=593665 M2M89_RS09065 WP_041850821.1 1756460..1758343(+) (hexB) [Bacillus subtilis strain S16]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHASSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPEKKVPEKSTAPSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQKQILEVSDVSAKEPDTFEQECHEGQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=593665 M2M89_RS09065 WP_041850821.1 1756460..1758343(+) (hexB) [Bacillus subtilis strain S16]
GTGGCAAAAGTCATCCAACTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGCGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAAGAATTGCCACCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGAAACAAATCCTTGAGGTGTCCGATGTTTCAGCGAAAGAGCCAGATACATTTGAGCAGGAATGCCATGAGGG
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCCAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTCGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATACACC
ATTCCACTTATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.047

100

0.474