Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MW405_RS10230 Genome accession   NZ_CP095518
Coordinates   2176141..2176731 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain GN02350     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2171141..2181731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MW405_RS10215 (MW405_10215) uhpT 2171781..2173172 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  MW405_RS10220 (MW405_10220) uhpC 2173310..2174629 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  MW405_RS10225 (MW405_10225) uhpB 2174639..2176141 (-) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  MW405_RS10230 (MW405_10230) letA 2176141..2176731 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  MW405_RS10235 (MW405_10235) ilvN 2176804..2177094 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  MW405_RS10240 (MW405_10240) ilvB 2177098..2178786 (-) 1689 WP_000168473.1 acetolactate synthase large subunit -
  MW405_RS10245 (MW405_10245) ivbL 2178892..2178990 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  MW405_RS10250 (MW405_10250) ysdE 2179235..2179309 (-) 75 WP_211180519.1 protein YsdE -
  MW405_RS10255 (MW405_10255) emrD 2179391..2180575 (+) 1185 WP_001304999.1 multidrug efflux MFS transporter EmrD -
  MW405_RS10260 (MW405_10260) yidF 2180583..2181080 (-) 498 WP_000148035.1 radical SAM protein -
  MW405_RS10265 (MW405_10265) yidG 2181077..2181439 (-) 363 WP_001113442.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=583502 MW405_RS10230 WP_000633668.1 2176141..2176731(-) (letA) [Escherichia coli strain GN02350]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=583502 MW405_RS10230 WP_000633668.1 2176141..2176731(-) (letA) [Escherichia coli strain GN02350]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378