Detailed information NTG0581877

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: MP619_RS10490
• Genome accession: NZ_CP095081
• Coordinates: 2105277..2106017 (-)
• Length: 246 a.a.
• NCBI ID: WP_129556294.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain WJ001
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 2100277..2111017

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MP619_RS10470 (MP619_10440)	-	2101382..2102377 (-)	996	WP_268227770.1	IS30 family transposase	-
MP619_RS10475 (MP619_10445)	jag	2102655..2103569 (-)	915	WP_129556293.1	RNA-binding cell elongation regulator Jag/EloR	-
MP619_RS10480 (MP619_10450)	-	2103581..2104408 (-)	828	WP_111679436.1	YidC/Oxa1 family membrane protein insertase	-
MP619_RS10485 (MP619_10455)	rnpA	2104374..2104733 (-)	360	WP_003056083.1	ribonuclease P protein component	-
MP619_RS10490 (MP619_10460)	comE/blpR	2105277..2106017 (-)	741	WP_129556294.1	LytTR family DNA-binding domain-containing protein	Regulator
MP619_RS10495 (MP619_10465)	-	2106021..2107304 (-)	1284	WP_129556295.1	sensor histidine kinase	-
MP619_RS10500 (MP619_10470)	-	2107305..2108648 (-)	1344	WP_129556296.1	GHKL domain-containing protein	-
MP619_RS10505 (MP619_10475)	-	2108801..2109823 (+)	1023	WP_129555386.1	IS30 family transposase	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28934.26 Da
• Isoelectric Point: 4.8691

>NTDB_id=581877 MP619_RS10490 WP_129556294.1 2105277..2106017(-) (comE/blpR) [Streptococcus dysgalactiae strain WJ001]
MMNIFILEDDFIQQTRIESVVADILEEAKIPCNQLEVFANPHKLFESIQERGDHQLYFLDIEIGAEDRRGLELAADIRQK
DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDKEQFRDQIEECIRYTYEMMSSRESEDMFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQLLYFDNGDSCMVSRLKMKCLFE
KWEALH

Nucleotide

• Length: 741 bp

>NTDB_id=581877 MP619_RS10490 WP_129556294.1 2105277..2106017(-) (comE/blpR) [Streptococcus dysgalactiae strain WJ001]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATCCAACAGACACGTATTGAATCTGTAGTGGCAGACATCTTGGAAGA
AGCTAAAATCCCTTGTAATCAGCTAGAAGTGTTTGCCAATCCTCATAAATTATTTGAAAGCATTCAAGAAAGAGGCGACC
ACCAGTTATATTTTTTAGACATTGAGATTGGTGCTGAGGATCGCCGAGGGCTTGAATTGGCAGCAGATATTCGACAAAAA
GACCCCAATGCGGTCATTGTGTTTGTTACCACACATTCTGAATTTGCTCCAATTTCTTTTAAATACAAAGTGTCTGCCTT
AGATTTTATTGACAAAGCAGTTGATAAGGAACAATTCAGGGATCAGATTGAAGAATGTATCCGCTATACCTATGAGATGA
TGTCTAGCCGAGAATCAGAAGACATGTTTTTATTTGAGACCCCTCAGACAAGGTTGAAATTACCTTACAAAGATATCCTT
TATTTTGCCACTGCTACGACACCCCACAAGGTGTGTTTGTGGACTCAGACGGAGAGACTGGAGTTTTATGGCAATTTATC
TGAGATACAAGCTGTGGCTCCAAAGCTTTTCTTATGCCATAGATCTTACTTGGTTAATCTAGATAAGGTTGTGCGTATTG
ATAAATCCAAACAGCTCCTTTATTTTGATAATGGGGATTCCTGCATGGTCTCACGCTTAAAAATGAAATGCCTTTTTGAA
AAATGGGAGGCCTTACATTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.117	97.154	0.467
comE/comE1	Streptococcus equinus JB1	42.857	96.748	0.415
comE/comE2	Streptococcus equinus JB1	40.408	99.593	0.402
comE/comE2	Streptococcus gordonii strain NCTC7865	39.113	100	0.394
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.113	100	0.394
comE	Streptococcus pneumoniae Rx1	36.929	97.967	0.362
comE	Streptococcus pneumoniae D39	36.929	97.967	0.362
comE	Streptococcus pneumoniae R6	36.929	97.967	0.362
comE	Streptococcus pneumoniae TIGR4	36.929	97.967	0.362
comE	Streptococcus mitis NCTC 12261	36.929	97.967	0.362
comE	Streptococcus mitis SK321	36.929	97.967	0.362