Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   I6L88_RS00350 Genome accession   NZ_CP077404
Coordinates   67726..69051 (+) Length   441 a.a.
NCBI ID   WP_002280233.1    Uniprot ID   -
Organism   Streptococcus mutans strain FDAARGOS 1458     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 62726..74051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L88_RS00325 (I6L88_00325) dnaI 62888..63787 (+) 900 WP_002280235.1 primosomal protein DnaI -
  I6L88_RS00330 (I6L88_00330) der 63800..65110 (+) 1311 WP_002265452.1 ribosome biogenesis GTPase Der -
  I6L88_RS00335 (I6L88_00335) - 65185..65811 (+) 627 WP_002265453.1 hypothetical protein -
  I6L88_RS00340 (I6L88_00340) - 65858..66496 (+) 639 WP_002265117.1 VTT domain-containing protein -
  I6L88_RS00345 (I6L88_00345) comE/blpR 66977..67729 (+) 753 WP_002280234.1 response regulator transcription factor Regulator
  I6L88_RS00350 (I6L88_00350) comD/blpH 67726..69051 (+) 1326 WP_002280233.1 sensor histidine kinase Regulator
  I6L88_RS00355 (I6L88_00355) comC/blpC 69188..69334 (-) 147 WP_002280232.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  I6L88_RS00360 (I6L88_00360) - 69601..69822 (+) 222 WP_002312090.1 Blp family class II bacteriocin -
  I6L88_RS00365 (I6L88_00365) - 69853..70071 (+) 219 WP_025985888.1 Blp family class II bacteriocin -
  I6L88_RS00370 (I6L88_00370) - 70157..70561 (+) 405 WP_002280427.1 hypothetical protein -
  I6L88_RS09970 - 70684..70896 (-) 213 Protein_74 IS3 family transposase -
  I6L88_RS00375 (I6L88_00375) - 71336..71500 (+) 165 WP_002265308.1 hypothetical protein -
  I6L88_RS00380 (I6L88_00380) - 71884..72075 (+) 192 WP_002312088.1 Blp family class II bacteriocin -
  I6L88_RS00385 (I6L88_00385) - 72239..72427 (+) 189 WP_002280338.1 Blp family class II bacteriocin -
  I6L88_RS00390 (I6L88_00390) - 72912..73940 (+) 1029 WP_002280337.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50525.74 Da        Isoelectric Point: 9.8155

>NTDB_id=581283 I6L88_RS00350 WP_002280233.1 67726..69051(+) (comD/blpH) [Streptococcus mutans strain FDAARGOS 1458]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGTQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYIIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSGKIQLPDMELLDFITILSILCDNAIEAALESLKPEIQLAFFKKNGSIVFIIQNSSKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIMK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=581283 I6L88_RS00350 WP_002280233.1 67726..69051(+) (comD/blpH) [Streptococcus mutans strain FDAARGOS 1458]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAACTCAAGGAATTGTAATGGACAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATATTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTATCAGCAAAAATCTTAGAAGCTCAAAATAAA
AAAATTGCTGTCAATGTAGAGGTCTCAGGTAAAATACAGCTGCCTGATATGGAGTTGCTTGATTTCATTACTATACTTTC
TATCTTGTGCGATAATGCTATTGAGGCCGCTCTCGAATCACTAAAACCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATCCAGAATTCCTCCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATGAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

97.506

100

0.975