Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I6L84_RS03380 Genome accession   NZ_CP077224
Coordinates   672564..673964 (+) Length   466 a.a.
NCBI ID   WP_060553640.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 667564..678964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS03360 (I6L84_03360) - 667970..670513 (+) 2544 WP_060553643.1 M1 family metallopeptidase -
  I6L84_RS03365 (I6L84_03365) - 670570..671112 (-) 543 WP_060553642.1 biotin transporter BioY -
  I6L84_RS03370 (I6L84_03370) - 671332..671769 (+) 438 WP_060553641.1 hypothetical protein -
  I6L84_RS03375 (I6L84_03375) ciaR 671900..672574 (+) 675 WP_008808730.1 response regulator transcription factor Regulator
  I6L84_RS03380 (I6L84_03380) ciaH 672564..673964 (+) 1401 WP_060553640.1 cell wall metabolism sensor histidine kinase WalK Regulator
  I6L84_RS03385 (I6L84_03385) - 673966..674892 (+) 927 WP_060553639.1 ketopantoate reductase family protein -
  I6L84_RS03390 (I6L84_03390) - 674916..676367 (-) 1452 WP_060553638.1 alpha-amylase -
  I6L84_RS03395 (I6L84_03395) rpsT 676598..676846 (-) 249 WP_008808726.1 30S ribosomal protein S20 -
  I6L84_RS03400 (I6L84_03400) coaA 676943..677863 (-) 921 WP_048779535.1 type I pantothenate kinase -
  I6L84_RS03405 (I6L84_03405) - 677969..678562 (+) 594 WP_060553637.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 466 a.a.        Molecular weight: 53142.24 Da        Isoelectric Point: 9.5727

>NTDB_id=580009 I6L84_RS03380 WP_060553640.1 672564..673964(+) (ciaH) [Streptococcus gordonii strain FDAARGOS 1454]
MLNKLRRTFYADDFSYFIRYFGVFTLIFSAMTLLIIQIMRSGLYTTVDDNLKSLSQNPRSVLHLALARAANMQPTIDEGQ
SSDDVSRPQDAPDPGPMDNLKVNSNTEAVLFDEDLKPLTTADHFLSLKKISIKKKDVGKIIQTTLKNNYGQEELYRMLVF
EINPSEFLSGNLLNKVKYAAVLINVNQLEQTSQNHEQIIVIVMISFWLISIIASIYLARVSVKPLMDSMQKQKSFVENAS
HELRTPLAVLQNRLETLFRKPEATIMESSENIASSLEEVRNMRMLTTNLLNLARRDDGIKAEIAEVEPEFFTTTFANYEI
IADENEKVFVFENHINHNIKTDRTLLKQLMTILFDNAVKYTEEDGVIKFIVWSKDRSLYLRVSDNGPGINNEDKKKIFDR
FYRVDKARTRQKGGFGLGLSLAKQIADALKGTITVKDNRPKGTIFEVKISIKSESKKKSTKLIGNK

Nucleotide


Download         Length: 1401 bp        

>NTDB_id=580009 I6L84_RS03380 WP_060553640.1 672564..673964(+) (ciaH) [Streptococcus gordonii strain FDAARGOS 1454]
ATGCTGAATAAACTTAGACGAACTTTTTATGCGGATGATTTTTCATATTTCATTCGCTATTTTGGTGTATTCACACTGAT
TTTCTCGGCCATGACTCTTTTAATCATTCAGATTATGCGCTCAGGACTCTATACAACCGTTGACGATAATTTAAAAAGTT
TAAGTCAGAATCCCAGATCTGTTCTCCACCTTGCTTTGGCTCGTGCAGCCAATATGCAACCGACGATTGATGAAGGTCAG
TCATCTGATGATGTATCTAGACCACAAGACGCACCAGACCCTGGACCAATGGATAATCTGAAGGTGAATTCGAACACTGA
AGCTGTCTTGTTTGATGAAGACTTGAAACCATTGACTACTGCAGATCATTTTCTTAGTTTAAAAAAGATTTCAATCAAGA
AAAAGGATGTAGGTAAAATTATTCAGACTACTTTGAAAAACAACTATGGTCAAGAAGAACTCTATCGTATGTTGGTTTTT
GAGATTAATCCAAGCGAATTCTTATCTGGGAATCTTTTGAACAAAGTTAAATATGCAGCAGTCCTGATTAATGTCAATCA
GTTGGAGCAAACCAGTCAGAATCATGAACAGATTATTGTCATTGTTATGATTAGCTTTTGGTTAATCTCAATTATTGCTA
GTATCTATTTGGCTCGTGTCAGTGTGAAGCCTCTGATGGACAGTATGCAGAAACAAAAATCTTTTGTTGAAAATGCAAGC
CATGAGTTGCGTACTCCTTTAGCCGTTTTGCAAAACCGCTTGGAAACTCTTTTCCGAAAACCCGAAGCTACCATTATGGA
ATCAAGCGAAAATATTGCCTCCAGTCTGGAAGAAGTTCGGAATATGCGGATGCTAACAACTAATCTATTGAATCTTGCAA
GAAGAGATGATGGCATTAAGGCTGAAATTGCTGAAGTTGAACCAGAATTTTTCACTACAACATTTGCCAACTATGAAATC
ATTGCGGATGAAAACGAGAAAGTATTTGTCTTTGAAAACCATATTAACCACAATATCAAGACAGACAGAACACTTCTAAA
ACAGCTGATGACCATTCTCTTTGATAATGCTGTAAAATATACGGAAGAAGATGGGGTTATTAAGTTTATAGTATGGTCAA
AAGACCGTTCTCTTTACTTACGAGTGTCTGATAACGGACCTGGAATCAATAATGAAGACAAAAAGAAAATTTTTGATCGT
TTTTATAGGGTTGATAAAGCCAGAACAAGACAAAAGGGTGGTTTTGGTCTAGGTCTATCCCTTGCAAAACAAATTGCCGA
TGCTCTAAAGGGTACAATTACTGTTAAAGATAATAGACCGAAAGGTACCATTTTTGAAGTCAAAATTTCCATTAAATCAG
AAAGCAAGAAAAAATCAACTAAGCTAATAGGAAATAAATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(342-449)

His Kinase A (phospho-acceptor) domain (HisKA)

(233-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae D39

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae R6

66.594

98.283

0.655
  ciaH Streptococcus pneumoniae TIGR4

66.594

98.283

0.655
  ciaH Streptococcus mutans UA159

54.343

96.352

0.524