Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   CCX78_RS08010 Genome accession   NZ_AP017931
Coordinates   1540394..1542355 (-) Length   653 a.a.
NCBI ID   WP_096585417.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain LK-145     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1535394..1547355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCX78_RS07985 (LASAK_01571) - 1535636..1536157 (-) 522 WP_231952325.1 GNAT family N-acetyltransferase -
  CCX78_RS07990 (LASAK_01572) queA 1536184..1537215 (-) 1032 WP_011374077.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  CCX78_RS07995 (LASAK_01573) ruvB 1537230..1538237 (-) 1008 WP_011374076.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  CCX78_RS08000 (LASAK_01574) ruvA 1538250..1538861 (-) 612 WP_011374075.1 Holliday junction branch migration protein RuvA Machinery gene
  CCX78_RS10340 - 1539272..1539833 (-) 562 Protein_1533 TIGR00730 family Rossman fold protein -
  CCX78_RS10345 (LASAK_01577) - 1539849..1540394 (-) 546 WP_056947792.1 Maf family protein -
  CCX78_RS08010 (LASAK_01578) hexB 1540394..1542355 (-) 1962 WP_096585417.1 DNA mismatch repair endonuclease MutL Machinery gene
  CCX78_RS08015 (LASAK_01579) hexA 1542379..1544982 (-) 2604 WP_096585420.1 DNA mismatch repair protein MutS Machinery gene
  CCX78_RS08020 (LASAK_01580) - 1545004..1545810 (-) 807 WP_016264637.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 653 a.a.        Molecular weight: 72731.16 Da        Isoelectric Point: 5.4265

>NTDB_id=57781 CCX78_RS08010 WP_096585417.1 1540394..1542355(-) (hexB) [Latilactobacillus sakei strain LK-145]
MGKIHELSEILSNQIAAGEVIERPASVVKELVENAIDANSTQVDIVVEQAGLQMIQVIDNGDGIEPEDVPVAFKRHATSK
IATRQDLFKIQSLGFRGEALASIASVSDLTIETATADSLGTFAHFKGGLLEEQKTNPIRPGTAITVRDLFFNTPARLKYV
KTFQTELANIVDIVNRLAMSHPQIAFTLTNDDHLLLKTAGNNDLKQTIAGIYGVTMAKKLLAVSASDLDFKLTGYVSLPE
LTRATRNYLSILINGRFIKNYQLNKAIIKGYGSKLMVGRYPIAVLAIEMDPLLIDVNVHPTKQEVRLSKETALMTLIEGA
IKERLATENLIPDAMQNLKRTKTVDVDQLQMNLNQITQERRHPSGTVRPVSPMPAPTTKPVTPEIAETETPLAAPTAKVP
AMTPERPLFEQPQALAEWDQKYATEAVGKPFGDQVVDETDESDETVVEPTVRFPELRYIGQLHSTFLLAEGEDGFYILDQ
HAAQERIKYEYYREKIGEVSTSVQNLLVPLVLEYPNSDALKIQEKTELLAAVGIQLENFGQNSFVVHSHPTWIEQGQEEM
TIRGMIDDVLKDGRISIAQFREKTAIMMSCKQSIKAHHHLDDAQAKALLADLAKTENPFNCPHGRPVLIHYTQKDLEKMF
KRIQEPHHSWEGE

Nucleotide


Download         Length: 1962 bp        

>NTDB_id=57781 CCX78_RS08010 WP_096585417.1 1540394..1542355(-) (hexB) [Latilactobacillus sakei strain LK-145]
ATGGGGAAAATTCATGAACTGTCGGAAATTCTAAGTAATCAAATTGCGGCGGGGGAAGTGATTGAACGCCCCGCCTCAGT
GGTCAAGGAATTGGTTGAAAACGCGATTGATGCCAATAGTACGCAAGTCGATATTGTTGTTGAACAGGCCGGTTTACAGA
TGATTCAAGTGATCGATAACGGTGACGGGATTGAGCCAGAAGATGTGCCAGTCGCCTTTAAACGACATGCCACCAGTAAG
ATTGCGACTCGGCAAGATTTGTTCAAGATTCAATCGCTAGGGTTTCGGGGCGAAGCGTTAGCTAGTATCGCGTCCGTTTC
TGATTTAACGATTGAAACGGCAACTGCGGACTCTCTAGGAACCTTTGCTCATTTTAAGGGTGGTCTGTTAGAGGAACAAA
AAACAAATCCGATTCGACCAGGGACGGCGATTACGGTGCGGGATTTATTCTTTAATACACCGGCACGATTGAAATACGTG
AAGACTTTTCAAACCGAATTGGCGAATATCGTCGATATCGTCAATCGGCTAGCAATGAGTCATCCACAGATTGCTTTCAC
GCTAACCAATGATGACCATCTACTTTTAAAAACGGCCGGCAACAATGACTTAAAACAAACGATTGCTGGTATTTATGGCG
TCACCATGGCCAAGAAACTCTTAGCCGTGAGTGCTTCGGATTTAGATTTTAAACTAACGGGCTACGTGTCATTGCCGGAA
TTAACGCGGGCAACGCGCAATTATTTGTCGATTTTAATTAATGGTCGGTTTATTAAAAATTACCAGTTGAATAAGGCCAT
TATCAAGGGCTACGGTTCTAAATTGATGGTCGGACGCTATCCAATCGCCGTCTTAGCGATTGAGATGGATCCGCTATTGA
TCGATGTCAACGTGCATCCAACAAAACAGGAAGTCCGCTTAAGCAAAGAAACGGCCTTGATGACCTTGATTGAAGGGGCA
ATCAAAGAAAGACTGGCAACCGAGAATTTAATTCCAGATGCCATGCAGAATTTGAAACGGACCAAGACGGTAGATGTTGA
TCAGCTCCAGATGAATTTAAACCAAATTACACAAGAAAGACGGCATCCAAGCGGTACGGTGCGACCAGTCAGTCCAATGC
CAGCCCCAACGACCAAACCGGTGACACCCGAAATTGCGGAAACCGAAACGCCGTTAGCCGCACCAACTGCTAAAGTGCCG
GCGATGACACCGGAGCGGCCCTTATTTGAGCAACCCCAGGCATTGGCCGAGTGGGATCAGAAGTACGCGACAGAGGCGGT
TGGGAAGCCATTTGGTGATCAAGTGGTAGACGAAACGGACGAAAGCGATGAAACCGTAGTCGAACCCACTGTTCGTTTCC
CAGAGTTACGCTACATTGGGCAACTGCATAGTACTTTCTTATTAGCGGAAGGCGAAGATGGCTTTTATATCTTGGATCAA
CACGCTGCGCAAGAACGGATTAAGTACGAGTATTACCGAGAAAAAATTGGGGAAGTCAGCACCTCTGTGCAAAACTTGTT
AGTACCGCTTGTTTTGGAATATCCGAATAGTGATGCGCTAAAGATTCAGGAAAAAACTGAACTCTTGGCGGCAGTCGGAA
TTCAATTAGAAAATTTCGGGCAGAATAGTTTTGTGGTCCACAGTCACCCAACTTGGATTGAACAGGGACAAGAGGAAATG
ACGATTCGTGGGATGATTGACGATGTTTTAAAAGACGGTCGCATTAGCATTGCCCAATTCCGTGAGAAGACGGCGATTAT
GATGAGCTGTAAGCAATCGATTAAAGCGCACCATCATTTAGATGATGCCCAGGCCAAAGCGCTTCTGGCTGATCTAGCGA
AGACTGAGAATCCGTTTAATTGTCCCCATGGGCGCCCGGTTTTGATTCACTACACGCAAAAAGATTTGGAAAAGATGTTT
AAACGGATTCAAGAACCACATCATAGTTGGGAGGGCGAATAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(456-600)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

50.608

100

0.51

Multiple sequence alignment