Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   MAK07_RS06970 Genome accession   NZ_CP091875
Coordinates   1303814..1304587 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain MN8     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1298814..1309587
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MAK07_RS06935 (MAK07_06215) - 1299067..1299837 (-) 771 WP_000473705.1 isoprenyl transferase -
  MAK07_RS06940 (MAK07_06210) frr 1300210..1300764 (-) 555 WP_001280006.1 ribosome recycling factor -
  MAK07_RS06945 (MAK07_06205) pyrH 1300783..1301505 (-) 723 WP_000057330.1 UMP kinase -
  MAK07_RS06950 (MAK07_06200) tsf 1301642..1302523 (-) 882 WP_000201387.1 translation elongation factor Ts -
  MAK07_RS06955 (MAK07_06195) - 1302558..1302671 (-) 114 WP_001791405.1 hypothetical protein -
  MAK07_RS06960 (MAK07_06190) rpsB 1302705..1303472 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  MAK07_RS06965 (MAK07_06185) - 1303671..1303763 (-) 93 WP_031788481.1 hypothetical protein -
  MAK07_RS06970 (MAK07_06180) codY 1303814..1304587 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  MAK07_RS06975 (MAK07_06175) hslU 1304612..1306015 (-) 1404 WP_000379051.1 ATP-dependent protease ATPase subunit HslU -
  MAK07_RS06980 (MAK07_06170) hslV 1306081..1306626 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  MAK07_RS06985 (MAK07_06165) xerC 1306623..1307519 (-) 897 WP_001015609.1 tyrosine recombinase XerC -
  MAK07_RS06990 (MAK07_06160) trmFO 1307937..1309244 (-) 1308 WP_000195263.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=563817 MAK07_RS06970 WP_000055337.1 1303814..1304587(-) (codY) [Staphylococcus aureus strain MN8]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=563817 MAK07_RS06970 WP_000055337.1 1303814..1304587(-) (codY) [Staphylococcus aureus strain MN8]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428