Detailed information NTG0561708

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV51_RS08380
• Genome accession: NZ_CP073869
• Coordinates: 1768216..1769262 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1279591
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1763216..1774262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV51_RS08350 (KFV51_08390)	-	1763600..1764841 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV51_RS08355 (KFV51_08395)	-	1764843..1765058 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV51_RS08360 (KFV51_08400)	-	1765199..1765663 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV51_RS08365 (KFV51_08405)	-	1765671..1765955 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV51_RS08370 (KFV51_08410)	-	1766362..1767540 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV51_RS08375 (KFV51_08415)	vraR	1767597..1768226 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV51_RS08380 (KFV51_08420)	vraS	1768216..1769262 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV51_RS08385 (KFV51_08425)	liaF	1769259..1769960 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV51_RS08390 (KFV51_08430)	-	1769975..1770361 (-)	387	WP_001830382.1	hypothetical protein	-
KFV51_RS08395 (KFV51_08435)	map	1770519..1771274 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV51_RS08400 (KFV51_08440)	-	1771448..1772434 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV51_RS08405 (KFV51_08445)	-	1772585..1773121 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561708 KFV51_RS08380 WP_001830374.1 1768216..1769262(-) (vraS) [Staphylococcus epidermidis strain B1279591]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561708 KFV51_RS08380 WP_001830374.1 1768216..1769262(-) (vraS) [Staphylococcus epidermidis strain B1279591]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92