Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV45_RS00610 | Genome accession | NZ_CP073862 |
| Coordinates | 109610..110956 (-) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus epidermidis strain B1276219 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 62295..110956 | 109610..110956 | within | 0 |
Gene organization within MGE regions
Location: 62295..110956
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV45_RS00355 (KFV45_00355) | ccrB | 62295..63923 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV45_RS00360 (KFV45_00360) | ccrA | 63920..65281 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV45_RS00365 (KFV45_00365) | - | 65468..66097 (-) | 630 | Protein_55 | hypothetical protein | - |
| KFV45_RS00370 (KFV45_00370) | - | 66106..66444 (+) | 339 | Protein_56 | recombinase family protein | - |
| KFV45_RS00375 (KFV45_00375) | - | 66556..66915 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV45_RS00380 (KFV45_00380) | - | 67122..67448 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV45_RS00385 (KFV45_00385) | - | 67778..69703 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV45_RS00390 (KFV45_00390) | - | 70955..71260 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV45_RS00395 (KFV45_00395) | - | 71458..72321 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV45_RS00400 (KFV45_00400) | - | 72429..73904 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV45_RS00405 (KFV45_00405) | - | 74131..75231 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV45_RS00410 (KFV45_00410) | - | 75224..75595 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV45_RS00415 (KFV45_00415) | - | 75592..77235 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV45_RS00420 (KFV45_00420) | - | 77462..79138 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV45_RS00425 (KFV45_00425) | - | 79244..79582 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV45_RS00430 (KFV45_00430) | - | 79678..79989 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV45_RS00435 (KFV45_00435) | - | 80005..80511 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV45_RS00440 (KFV45_00440) | - | 80539..80985 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV45_RS00445 (KFV45_00445) | - | 81155..82027 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV45_RS00450 (KFV45_00450) | - | 82079..82369 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV45_RS00460 (KFV45_00460) | - | 82592..82747 (+) | 156 | Protein_73 | metal-sensing transcriptional repressor | - |
| KFV45_RS00465 (KFV45_00465) | - | 82744..83502 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV45_RS00470 (KFV45_00470) | - | 83672..83881 (+) | 210 | Protein_75 | heavy metal translocating P-type ATPase | - |
| KFV45_RS00475 (KFV45_00475) | - | 83899..84444 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV45_RS00480 (KFV45_00480) | - | 84887..86143 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV45_RS00485 (KFV45_00485) | - | 86588..87262 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV45_RS00490 (KFV45_00490) | - | 87346..87687 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV45_RS00495 (KFV45_00495) | - | 88484..89227 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV45_RS00500 (KFV45_00500) | - | 89324..89752 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV45_RS00505 (KFV45_00505) | mecA | 89798..91807 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV45_RS00510 (KFV45_00510) | mecR1 | 91904..93661 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV45_RS00515 (KFV45_00515) | mecI | 93661..94032 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV45_RS00520 (KFV45_00520) | psm-mec | 94117..94185 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV45_RS00525 (KFV45_00525) | - | 94540..95649 (+) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KFV45_RS00530 (KFV45_00530) | cstB | 95763..97097 (-) | 1335 | Protein_87 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV45_RS00535 (KFV45_00535) | - | 97130..98194 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV45_RS00540 (KFV45_00540) | cstR | 98330..98590 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV45_RS00545 (KFV45_00545) | - | 98590..99228 (+) | 639 | Protein_90 | sulfite exporter TauE/SafE family protein | - |
| KFV45_RS00555 (KFV45_00555) | - | 99502..100118 (-) | 617 | Protein_91 | CadD family cadmium resistance transporter | - |
| KFV45_RS00560 (KFV45_00560) | - | 100199..102613 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV45_RS00565 (KFV45_00565) | - | 102606..102971 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV45_RS00570 (KFV45_00570) | - | 103209..103586 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV45_RS00575 (KFV45_00575) | - | 103593..105485 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV45_RS00580 (KFV45_00580) | - | 105680..106003 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV45_RS00585 (KFV45_00585) | - | 105996..106202 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV45_RS00590 (KFV45_00590) | - | 106204..106725 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV45_RS00595 (KFV45_00595) | - | 106744..107055 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV45_RS00600 (KFV45_00600) | - | 107140..107490 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV45_RS00605 (KFV45_00605) | ccrB | 107961..109589 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV45_RS00610 (KFV45_00610) | ccrA | 109610..110956 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=561572 KFV45_RS00610 WP_000816499.1 109610..110956(-) (ccrA) [Staphylococcus epidermidis strain B1276219]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=561572 KFV45_RS00610 WP_000816499.1 109610..110956(-) (ccrA) [Staphylococcus epidermidis strain B1276219]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |