Detailed information NTG0561180

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV52_RS08795
• Genome accession: NZ_CP073835
• Coordinates: 1805510..1806556 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1230143
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1800510..1811556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV52_RS08765 (KFV52_08775)	-	1800894..1802135 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV52_RS08770 (KFV52_08780)	-	1802137..1802352 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV52_RS08775 (KFV52_08785)	-	1802493..1802957 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV52_RS08780 (KFV52_08790)	-	1802965..1803249 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV52_RS08785 (KFV52_08795)	-	1803656..1804834 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV52_RS08790 (KFV52_08800)	vraR	1804891..1805520 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV52_RS08795 (KFV52_08805)	vraS	1805510..1806556 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV52_RS08800 (KFV52_08810)	liaF	1806553..1807254 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV52_RS08805 (KFV52_08815)	-	1807269..1807655 (-)	387	WP_001830382.1	hypothetical protein	-
KFV52_RS08810 (KFV52_08820)	map	1807813..1808568 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV52_RS08815 (KFV52_08825)	-	1808742..1809728 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV52_RS08820 (KFV52_08830)	-	1809879..1810415 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561180 KFV52_RS08795 WP_001830374.1 1805510..1806556(-) (vraS) [Staphylococcus epidermidis strain B1230143]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561180 KFV52_RS08795 WP_001830374.1 1805510..1806556(-) (vraS) [Staphylococcus epidermidis strain B1230143]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92