Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   SMUNUM_RS03865 Genome accession   NZ_AP014571
Coordinates   765214..767205 (+) Length   663 a.a.
NCBI ID   WP_002261961.1    Uniprot ID   Q8CWX7
Organism   Streptococcus mutans LP13     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 760214..772205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS03850 (SMNUM_0713) - 760983..761723 (-) 741 WP_286217420.1 amino acid ABC transporter ATP-binding protein -
  SMUNUM_RS03855 (SMNUM_0714) - 761723..763909 (-) 2187 WP_002261959.1 ABC transporter substrate-binding protein/permease -
  SMUNUM_RS03860 (SMNUM_0715) - 764100..765017 (+) 918 WP_002261960.1 CPBP family intramembrane glutamic endopeptidase -
  SMUNUM_RS03865 (SMNUM_0716) uvrB 765214..767205 (+) 1992 WP_002261961.1 excinuclease ABC subunit UvrB Machinery gene
  SMUNUM_RS03870 - 767345..767467 (-) 123 WP_255262718.1 hypothetical protein -
  SMUNUM_RS03875 - 767537..767869 (+) 333 WP_002261962.1 hypothetical protein -
  SMUNUM_RS03880 (SMNUM_0717) - 768173..769063 (+) 891 WP_002267623.1 helix-turn-helix domain-containing protein -
  SMUNUM_RS03885 (SMNUM_0718) - 769121..769585 (+) 465 WP_002261965.1 8-oxo-dGTP diphosphatase -
  SMUNUM_RS03890 (SMNUM_0719) - 769693..770508 (+) 816 WP_002261966.1 transporter substrate-binding domain-containing protein -
  SMUNUM_RS03895 (SMNUM_0720) - 770724..771860 (+) 1137 WP_002261967.1 aminotransferase -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 76025.94 Da        Isoelectric Point: 4.6232

>NTDB_id=55529 SMUNUM_RS03865 WP_002261961.1 765214..767205(+) (uvrB) [Streptococcus mutans LP13]
MIDRKDNNQFHLVSKYEPSGDQPEAIEALVDNIEGGEKAQILKGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPSQEISRDQLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGRVL
GEVDHLAIFPATHFMTNDEHMEVAIAKIQKEMKEQVRLFEAEGKLIEAQRIRQRTEYDVEMLREMGYTSGVENYSRHMDG
RSEGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTDTVIEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINTRADKGERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSQGHVIMYADT
VTQSMRRAIDETHRRRQIQMAYNEEHGIIPQTIKKDIRDLIAITKANDSEVAEEAVDYNAMTKSERQEAIKKLQKQMQEA
AELLDFELAAQIRDMVLELKAMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=55529 SMUNUM_RS03865 WP_002261961.1 765214..767205(+) (uvrB) [Streptococcus mutans LP13]
ATGATAGATAGGAAAGATAATAACCAGTTTCATCTGGTTTCAAAATATGAGCCGTCTGGTGATCAGCCTGAGGCCATTGA
GGCTTTGGTTGACAATATTGAAGGTGGTGAGAAAGCGCAAATTCTCAAAGGGGCGACTGGGACGGGAAAAACCTATACCA
TGAGCCAAGTTATTCAAAAAGTCAATAAACCGACTTTAGTCATCGCTCATAATAAAACTCTAGCTGGTCAGCTTTACGGT
GAATTTAAAGAATTTTTCCCAGATAATGCAGTTGAGTATTTTGTTTCTTACTATGATTATTATCAGCCTGAAGCCTATGT
GCCATCAAGTGATACCTATATTGAAAAGGATAGTTCAGTTAATGATGAGATTGATAAGCTCCGACATTCGGCAACATCTG
CCCTTTTGGAACGCAATGATGTCATTGTCGTAGCATCCGTCTCCTGTATTTATGGTTTAGGGTCACCCAAGGAATATGCA
GATAGCGTGGTTAGTCTGCGGCCCAGTCAGGAGATTTCTCGCGACCAACTGTTAAATGATTTGGTAGATATTCAGTTTGA
GCGCAACGATATTGATTTCCAGCGGGGACGTTTTCGTGTGCGCGGCGATGTGGTGGAAATTTTTCCAGCATCACGTGATG
AACATGCTTTTCGTGTGGAATTTTTCGGTGATGAGATTGATCGTATCAGAGAAATTGAGAGTTTAACAGGTCGTGTTCTT
GGTGAAGTAGATCACTTGGCTATTTTTCCAGCAACTCACTTTATGACTAACGATGAGCACATGGAAGTGGCTATTGCCAA
GATTCAAAAGGAAATGAAAGAGCAAGTCAGGCTTTTTGAAGCAGAAGGGAAATTGATTGAAGCACAGCGTATTCGCCAAA
GAACAGAGTATGATGTGGAAATGCTGCGGGAGATGGGCTATACTAGCGGCGTTGAAAACTATTCGCGTCATATGGATGGC
CGCAGTGAGGGAGAACCGCCTTATACACTTCTTGACTTTTTTCCAGAGGATTTCCTCATCATGATTGATGAAAGCCACAT
GACTATGGGGCAGATTAAAGGTATGTATAATGGTGACCGATCGCGCAAGGAGATGTTGGTCAACTATGGTTTTCGTCTGC
CAAGTGCGCTGGACAATCGACCGCTGCGTCGAGAAGAATTTGAAAGCCATGTCCATCAGATTGTCTATGTTTCAGCAACA
CCAGGTGACTATGAGATGGAGCAGACGGACACGGTTATTGAGCAAATTATCCGTCCGACTGGTCTCTTGGACCCAGAAGT
GGAAGTTCGGCCAACCATGGGACAAATGGATGACTTGCTGGGTGAAATCAATACGCGTGCTGATAAGGGCGAGCGGACCT
TTATTACAACCTTAACCAAGAAAATGGCGGAAGATTTGACTGACTACCTCAAGGAAATGGGTGTCAAGGTCAAGTACATG
CATTCTGACATCAAGACTCTGGAACGTACTGAAATTATCCGCGACCTTCGTTTAGGTGTTTTTGATGTTCTTATCGGTAT
CAATTTGCTGCGCGAAGGTATTGATGTGCCAGAGGTTAGTCTGGTTGCCATTCTTGATGCAGACAAAGAAGGTTTTCTCC
GCAATGAACGTGGTCTTATCCAGACCATTGGACGGGCTGCGCGCAACAGTCAAGGACATGTTATTATGTATGCTGATACT
GTGACGCAGTCCATGCGTCGCGCTATTGATGAGACCCACCGCCGCCGCCAAATCCAAATGGCTTACAATGAAGAGCATGG
TATTATTCCACAAACCATCAAAAAAGATATCCGCGATCTTATCGCGATTACAAAAGCAAATGACTCTGAAGTGGCTGAGG
AGGCTGTGGATTATAATGCAATGACCAAATCTGAACGTCAAGAAGCCATCAAGAAACTGCAAAAACAAATGCAAGAAGCA
GCTGAACTGCTTGATTTTGAACTGGCTGCTCAAATCCGCGATATGGTTTTAGAATTGAAGGCGATGGATTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(628-661)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8CWX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

89.291

100

0.893
  uvrB Streptococcus pneumoniae D39

89.291

100

0.893
  uvrB Streptococcus pneumoniae TIGR4

89.14

100

0.891

Multiple sequence alignment