Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D25_RS03770 Genome accession   NZ_CP071986
Coordinates   797640..799424 (-) Length   594 a.a.
NCBI ID   WP_209554360.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5124     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 792640..804424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D25_RS03740 (J5D25_03740) - 793003..793251 (+) 249 WP_000790555.1 RNA-binding protein -
  J5D25_RS03745 (J5D25_03745) - 793467..794288 (-) 822 WP_209554356.1 glycosyltransferase family 25 protein -
  J5D25_RS03750 (J5D25_03750) trxB 794669..795604 (-) 936 WP_209554358.1 thioredoxin-disulfide reductase -
  J5D25_RS03755 (J5D25_03755) trxA 795610..795930 (-) 321 WP_000020204.1 thioredoxin -
  J5D25_RS03760 (J5D25_03760) - 796019..796363 (-) 345 WP_001210428.1 YraN family protein -
  J5D25_RS03765 (J5D25_03765) - 796364..797629 (-) 1266 WP_187837525.1 homoserine dehydrogenase -
  J5D25_RS03770 (J5D25_03770) uvrC 797640..799424 (-) 1785 WP_209554360.1 excinuclease ABC subunit UvrC Machinery gene
  J5D25_RS03775 (J5D25_03775) - 799425..799886 (-) 462 WP_000437152.1 hypothetical protein -
  J5D25_RS03780 (J5D25_03780) - 799878..800057 (+) 180 WP_000468798.1 hypothetical protein -
  J5D25_RS03785 (J5D25_03785) - 800061..800711 (-) 651 WP_209554361.1 ATP-binding cassette domain-containing protein -
  J5D25_RS03790 (J5D25_03790) - 800715..802376 (-) 1662 WP_209554363.1 ABC transporter permease/substrate-binding protein -
  J5D25_RS03795 (J5D25_03795) - 802490..802927 (-) 438 WP_001039460.1 hypothetical protein -
  J5D25_RS03800 (J5D25_03800) motB 802933..803706 (-) 774 WP_001085349.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68593.71 Da        Isoelectric Point: 9.7158

>NTDB_id=549736 J5D25_RS03770 WP_209554360.1 797640..799424(-) (uvrC) [Helicobacter pylori strain MT5124]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRTSLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSINGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNIKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549736 J5D25_RS03770 WP_209554360.1 797640..799424(-) (uvrC) [Helicobacter pylori strain MT5124]
ATGGCTGATTTATTGTCTAGTTTGAAAAACCTTTCTAATAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCTA
ATCATCGCACAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGTGGGGCTAAGGACATTTTGGACAGCTTGTATGAATTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATCTGGATATTTTTGCTTTTTATGGCGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCATCAATGGGTTTGACA
CTGATGAAGCGATGAAGCAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGT
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTATATGAAAACAATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCAACACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATAAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAAGAAAAAAA
CGCCGTTTTGAAAAAACGAAATTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.796

99.832

0.966