Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | I6J34_RS06540 | Genome accession | NZ_CP069582 |
| Coordinates | 1268399..1270030 (-) | Length | 543 a.a. |
| NCBI ID | WP_115359439.1 | Uniprot ID | - |
| Organism | Staphylococcus carnosus strain FDAARGOS_1204 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 1228478..1303654 | 1268399..1270030 | within | 0 |
Gene organization within MGE regions
Location: 1228478..1303654
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J34_RS06355 (I6J34_06355) | ccrB | 1228478..1230103 (-) | 1626 | WP_103211952.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J34_RS06360 (I6J34_06360) | ccrA | 1230125..1231474 (-) | 1350 | WP_103211951.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I6J34_RS06365 (I6J34_06365) | - | 1231652..1231909 (-) | 258 | WP_103211950.1 | hypothetical protein | - |
| I6J34_RS06370 (I6J34_06370) | cch1 | 1231977..1233767 (-) | 1791 | WP_103211949.1 | cassette chromosome replicative helicase | - |
| I6J34_RS06375 (I6J34_06375) | - | 1233893..1235323 (-) | 1431 | WP_115359434.1 | DUF6038 family protein | - |
| I6J34_RS06380 (I6J34_06380) | - | 1235752..1236933 (+) | 1182 | WP_115359435.1 | PD-(D/E)XK nuclease family protein | - |
| I6J34_RS06385 (I6J34_06385) | - | 1237231..1237887 (+) | 657 | WP_115359436.1 | hypothetical protein | - |
| I6J34_RS13460 (I6J34_06390) | - | 1238059..1238502 (+) | 444 | WP_103211938.1 | Cthe_2314 family HEPN domain-containing protein | - |
| I6J34_RS13465 (I6J34_06395) | - | 1238549..1238791 (+) | 243 | WP_103211937.1 | Cthe_2314 family HEPN domain-containing protein | - |
| I6J34_RS06400 (I6J34_06400) | - | 1238844..1240169 (+) | 1326 | WP_115359437.1 | DUF6038 family protein | - |
| I6J34_RS06405 (I6J34_06405) | - | 1240380..1241480 (+) | 1101 | Protein_1234 | hypothetical protein | - |
| I6J34_RS06410 (I6J34_06410) | - | 1241473..1241841 (+) | 369 | WP_103211809.1 | hypothetical protein | - |
| I6J34_RS06415 (I6J34_06415) | - | 1241841..1243484 (+) | 1644 | WP_103211808.1 | DUF5906 domain-containing protein | - |
| I6J34_RS06420 (I6J34_06420) | ccrC | 1243709..1245385 (+) | 1677 | WP_103211807.1 | cassette chromosome recombinase CcrC | - |
| I6J34_RS06425 (I6J34_06425) | - | 1245491..1245829 (+) | 339 | WP_103211806.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J34_RS06430 (I6J34_06430) | - | 1245925..1246236 (+) | 312 | WP_053464988.1 | DUF960 family protein | - |
| I6J34_RS06435 (I6J34_06435) | - | 1246252..1246758 (+) | 507 | WP_044291531.1 | DUF1643 domain-containing protein | - |
| I6J34_RS06440 (I6J34_06440) | - | 1246779..1247210 (+) | 432 | WP_235893312.1 | JAB domain-containing protein | - |
| I6J34_RS06445 (I6J34_06445) | - | 1247394..1248266 (+) | 873 | WP_103211805.1 | HTH domain-containing protein | - |
| I6J34_RS06450 (I6J34_06450) | - | 1248323..1248613 (+) | 291 | WP_103211804.1 | hypothetical protein | - |
| I6J34_RS06455 (I6J34_06455) | - | 1248636..1249118 (+) | 483 | WP_103211803.1 | hypothetical protein | - |
| I6J34_RS06460 (I6J34_06460) | - | 1249254..1249856 (+) | 603 | WP_103211965.1 | hypothetical protein | - |
| I6J34_RS06465 (I6J34_06465) | - | 1250178..1250426 (+) | 249 | WP_235893315.1 | hypothetical protein | - |
| I6J34_RS06470 (I6J34_06470) | galU | 1250720..1251589 (+) | 870 | WP_103211973.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| I6J34_RS06475 (I6J34_06475) | - | 1251610..1254483 (+) | 2874 | WP_115359438.1 | CDP-glycerol glycerophosphotransferase family protein | - |
| I6J34_RS13300 | - | 1254992..1256449 (+) | 1458 | WP_235893313.1 | DNA methyltransferase | - |
| I6J34_RS13305 | - | 1256442..1257740 (+) | 1299 | WP_235893314.1 | type IIL restriction-modification enzyme MmeI | - |
| I6J34_RS06485 (I6J34_06485) | - | 1257730..1259676 (+) | 1947 | WP_046099750.1 | DEAD/DEAH box helicase | - |
| I6J34_RS06490 (I6J34_06490) | - | 1259679..1260809 (+) | 1131 | WP_235318574.1 | GIY-YIG nuclease family protein | - |
| I6J34_RS06495 (I6J34_06495) | - | 1260903..1261124 (-) | 222 | WP_046099752.1 | hypothetical protein | - |
| I6J34_RS06500 (I6J34_06500) | - | 1261140..1261643 (-) | 504 | WP_046099753.1 | DUF1643 domain-containing protein | - |
| I6J34_RS06505 (I6J34_06505) | - | 1261659..1261970 (-) | 312 | WP_046099754.1 | DUF960 family protein | - |
| I6J34_RS06510 (I6J34_06510) | - | 1262057..1262407 (-) | 351 | WP_046099755.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J34_RS06515 (I6J34_06515) | - | 1262941..1263117 (-) | 177 | Protein_1257 | sodium:proline symporter | - |
| I6J34_RS06520 (I6J34_06520) | - | 1263385..1264833 (-) | 1449 | WP_046099757.1 | aldehyde dehydrogenase family protein | - |
| I6J34_RS06525 (I6J34_06525) | - | 1264999..1266108 (+) | 1110 | WP_046099758.1 | NAD(P)-dependent alcohol dehydrogenase | - |
| I6J34_RS06530 (I6J34_06530) | - | 1266956..1267150 (-) | 195 | WP_142382768.1 | hypothetical protein | - |
| I6J34_RS06535 (I6J34_06535) | - | 1267586..1267936 (-) | 351 | WP_046099759.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J34_RS06540 (I6J34_06540) | ccrB | 1268399..1270030 (-) | 1632 | WP_115359439.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J34_RS06545 (I6J34_06545) | ccrA | 1270051..1271400 (-) | 1350 | WP_103211957.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I6J34_RS06550 (I6J34_06550) | - | 1271592..1271867 (-) | 276 | WP_046099761.1 | hypothetical protein | - |
| I6J34_RS06555 (I6J34_06555) | cch1 | 1271936..1273723 (-) | 1788 | WP_046099762.1 | cassette chromosome replicative helicase | - |
| I6J34_RS06560 (I6J34_06560) | ssb | 1273723..1274016 (-) | 294 | WP_046099763.1 | cassette chromosome ssDNA-binding protein | - |
| I6J34_RS06565 (I6J34_06565) | - | 1274153..1275202 (+) | 1050 | WP_046099764.1 | hypothetical protein | - |
| I6J34_RS06570 (I6J34_06570) | - | 1275241..1276542 (+) | 1302 | WP_046099765.1 | ATP-binding protein | - |
| I6J34_RS13590 | - | 1276954..1277049 (+) | 96 | Protein_1269 | hypothetical protein | - |
| I6J34_RS06575 (I6J34_06575) | - | 1277065..1278399 (+) | 1335 | WP_420916158.1 | four-carbon acid sugar kinase family protein | - |
| I6J34_RS06580 (I6J34_06580) | - | 1278418..1279672 (+) | 1255 | Protein_1271 | gluconate:H+ symporter | - |
| I6J34_RS06585 (I6J34_06585) | - | 1280022..1280216 (+) | 195 | WP_142382762.1 | hypothetical protein | - |
| I6J34_RS06590 (I6J34_06590) | - | 1280565..1281302 (+) | 738 | WP_308669872.1 | GntR family transcriptional regulator | - |
| I6J34_RS06595 (I6J34_06595) | deoD | 1281645..1282352 (+) | 708 | WP_046099767.1 | purine-nucleoside phosphorylase | - |
| I6J34_RS06600 (I6J34_06600) | - | 1282365..1283720 (+) | 1356 | WP_103211845.1 | MFS transporter | - |
| I6J34_RS06605 (I6J34_06605) | deoC | 1283734..1284396 (+) | 663 | WP_046099769.1 | deoxyribose-phosphate aldolase | - |
| I6J34_RS06610 (I6J34_06610) | deoB | 1284425..1285603 (+) | 1179 | WP_046099770.1 | phosphopentomutase | - |
| I6J34_RS06615 (I6J34_06615) | - | 1285649..1285777 (-) | 129 | Protein_1278 | NAD-dependent protein deacylase | - |
| I6J34_RS06620 (I6J34_06620) | ccrB | 1286179..1287807 (-) | 1629 | WP_046099772.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J34_RS06625 (I6J34_06625) | ccrA | 1287828..1289177 (-) | 1350 | WP_046099773.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I6J34_RS06630 (I6J34_06630) | - | 1289563..1290336 (+) | 774 | WP_046099774.1 | acetoin reductase | - |
| I6J34_RS06635 (I6J34_06635) | - | 1290539..1291831 (+) | 1293 | WP_046099775.1 | NtaA/DmoA family FMN-dependent monooxygenase | - |
| I6J34_RS06640 (I6J34_06640) | - | 1292085..1294877 (+) | 2793 | WP_046099792.1 | type I restriction endonuclease subunit R | - |
| I6J34_RS06645 (I6J34_06645) | - | 1294967..1295548 (+) | 582 | WP_103211980.1 | restriction endonuclease subunit S | - |
| I6J34_RS06650 (I6J34_06650) | - | 1295549..1297105 (+) | 1557 | WP_046099794.1 | type I restriction-modification system subunit M | - |
| I6J34_RS13595 | - | 1297098..1297271 (+) | 174 | Protein_1286 | restriction endonuclease subunit S | - |
| I6J34_RS13600 | - | 1297587..1297758 (+) | 172 | Protein_1287 | restriction endonuclease subunit S | - |
| I6J34_RS06660 (I6J34_06660) | - | 1297911..1298324 (+) | 414 | WP_204111547.1 | restriction endonuclease subunit S | - |
| I6J34_RS06665 (I6J34_06665) | - | 1298375..1298623 (+) | 249 | WP_046099796.1 | hypothetical protein | - |
| I6J34_RS06670 (I6J34_06670) | - | 1298688..1298909 (-) | 222 | WP_046099797.1 | hypothetical protein | - |
| I6J34_RS06675 (I6J34_06675) | - | 1298924..1299424 (-) | 501 | WP_046099798.1 | DUF1643 domain-containing protein | - |
| I6J34_RS06680 (I6J34_06680) | - | 1299438..1299749 (-) | 312 | WP_103211969.1 | DUF960 family protein | - |
| I6J34_RS06685 (I6J34_06685) | - | 1299845..1300183 (-) | 339 | WP_115359440.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J34_RS06690 (I6J34_06690) | ccrB | 1300658..1302283 (-) | 1626 | WP_103211647.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J34_RS06695 (I6J34_06695) | ccrA | 1302305..1303654 (-) | 1350 | WP_103211648.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 543 a.a. Molecular weight: 62499.46 Da Isoelectric Point: 9.6504
>NTDB_id=535706 I6J34_RS06540 WP_115359439.1 1268399..1270030(-) (ccrB) [Staphylococcus carnosus strain FDAARGOS_1204]
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPALQRMLHDANKGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNTILENIYTGQHQRALEGYYQGN
LPLGYNNIPDNKKDLMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAK
YKDWNDKRRKGLNDKPVIAEGKHTPIISQSLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQEHQIDTSALNHDIAYKQQQYD
EVQIKLDNLIKTLEDNPDLTSVLKNTIHQYEKQLNDITNQINQLKQQQSAPKTIYDANEIATILRHIFKNIETMDKAQLK
ALYLTVIDHIDIRKDEHHKKQFYVTLKLNHEIIKQLFHNIPLDEVQLSTSSLLLSQTLYLPIS
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPALQRMLHDANKGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNTILENIYTGQHQRALEGYYQGN
LPLGYNNIPDNKKDLMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAK
YKDWNDKRRKGLNDKPVIAEGKHTPIISQSLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQEHQIDTSALNHDIAYKQQQYD
EVQIKLDNLIKTLEDNPDLTSVLKNTIHQYEKQLNDITNQINQLKQQQSAPKTIYDANEIATILRHIFKNIETMDKAQLK
ALYLTVIDHIDIRKDEHHKKQFYVTLKLNHEIIKQLFHNIPLDEVQLSTSSLLLSQTLYLPIS
Nucleotide
Download Length: 1632 bp
>NTDB_id=535706 I6J34_RS06540 WP_115359439.1 1268399..1270030(-) (ccrB) [Staphylococcus carnosus strain FDAARGOS_1204]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGACGGTCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGCACTTCAACGTATGTTACATGATGCGAATAAAGGTCATATTGATTGTGTTATG
GTGTATAAAACAAATCGACTCGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTGTCTGAGCGTATGGAAGTCAACACTTCTTCTGGTAAACTCATGTTACAAATACTTGCAAGTTTTTCCG
AATTTGAAAGAAATACCATTTTAGAGAATATTTACACCGGACAACATCAAAGAGCCTTAGAAGGCTATTACCAAGGTAAT
CTTCCTTTAGGATATAATAACATACCAGATAATAAAAAAGATTTGATGATTAATCAGCATGAAGCTAATATTGTGAAATA
TATTTTTGAATCTTACGCCAAAGGTCATGGTTATCGTAAAATTGCCAACGCACTCAATCATAAAGGTTATGTCACTAAGA
AAGGTAATCCTTTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAA
TACAAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAACCCGTAATTGCCGAAGGCAAACACACCCCTATTAT
TAGCCAATCATTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTTCATGGTAAAGGAACCA
ATATTTTAACTGGATTAATTTCGTGTCCCCAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGAT
GGTACTAAAAAACGCATTCGCTACTATTCGTGTAGTAACTTTCGTAATAAAGGGTCAAAAGTATGTTCTGCGAATAGTGT
CAGAGCCGATGTAATTGAAAAATATGTTATGGATCAAATACTCGAAATTGTTAAAAGCGACAAGGTTATCAAGCAAGTCG
TTGAGCGTGTCAATCAAGAACATCAAATTGATACGTCTGCACTCAATCATGATATCGCATATAAGCAACAACAATATGAT
GAGGTCCAAATCAAATTAGATAACTTGATAAAAACGCTTGAAGATAATCCAGACTTAACATCTGTGCTTAAAAATACGAT
TCATCAGTATGAAAAACAACTCAATGACATCACAAATCAAATCAATCAACTTAAGCAACAACAAAGTGCTCCCAAAACAA
TATATGACGCTAATGAGATTGCGACTATATTACGTCATATATTCAAAAATATCGAAACCATGGATAAAGCACAACTCAAA
GCACTATACCTTACGGTCATAGACCACATTGATATTCGTAAAGACGAACATCATAAAAAACAGTTCTACGTCACATTAAA
ACTCAATCATGAAATCATTAAACAACTCTTCCATAATATCCCTCTCGACGAAGTGCAACTCAGCACTTCGTCTTTATTAT
TATCTCAAACACTCTATTTGCCTATCTCATAA
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGACGGTCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGCACTTCAACGTATGTTACATGATGCGAATAAAGGTCATATTGATTGTGTTATG
GTGTATAAAACAAATCGACTCGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTGTCTGAGCGTATGGAAGTCAACACTTCTTCTGGTAAACTCATGTTACAAATACTTGCAAGTTTTTCCG
AATTTGAAAGAAATACCATTTTAGAGAATATTTACACCGGACAACATCAAAGAGCCTTAGAAGGCTATTACCAAGGTAAT
CTTCCTTTAGGATATAATAACATACCAGATAATAAAAAAGATTTGATGATTAATCAGCATGAAGCTAATATTGTGAAATA
TATTTTTGAATCTTACGCCAAAGGTCATGGTTATCGTAAAATTGCCAACGCACTCAATCATAAAGGTTATGTCACTAAGA
AAGGTAATCCTTTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAA
TACAAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAACCCGTAATTGCCGAAGGCAAACACACCCCTATTAT
TAGCCAATCATTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTTCATGGTAAAGGAACCA
ATATTTTAACTGGATTAATTTCGTGTCCCCAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGAT
GGTACTAAAAAACGCATTCGCTACTATTCGTGTAGTAACTTTCGTAATAAAGGGTCAAAAGTATGTTCTGCGAATAGTGT
CAGAGCCGATGTAATTGAAAAATATGTTATGGATCAAATACTCGAAATTGTTAAAAGCGACAAGGTTATCAAGCAAGTCG
TTGAGCGTGTCAATCAAGAACATCAAATTGATACGTCTGCACTCAATCATGATATCGCATATAAGCAACAACAATATGAT
GAGGTCCAAATCAAATTAGATAACTTGATAAAAACGCTTGAAGATAATCCAGACTTAACATCTGTGCTTAAAAATACGAT
TCATCAGTATGAAAAACAACTCAATGACATCACAAATCAAATCAATCAACTTAAGCAACAACAAAGTGCTCCCAAAACAA
TATATGACGCTAATGAGATTGCGACTATATTACGTCATATATTCAAAAATATCGAAACCATGGATAAAGCACAACTCAAA
GCACTATACCTTACGGTCATAGACCACATTGATATTCGTAAAGACGAACATCATAAAAAACAGTTCTACGTCACATTAAA
ACTCAATCATGAAATCATTAAACAACTCTTCCATAATATCCCTCTCGACGAAGTGCAACTCAGCACTTCGTCTTTATTAT
TATCTCAAACACTCTATTTGCCTATCTCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
82.657 |
99.816 |
0.825 |